Dronfield M W, Malone J D, Langman M J
Gut. 1977 Jan;18(1):33-6. doi: 10.1136/gut.18.1.33.
A double-blind controlled trial of oral zinc sulphate as adjuvant treatment in idiopathic ulcerative colitis or proctitis in relapse is reported. Fifty-one patients were treated, and the clinical and sigmoidoscopic improvement in the zinc treated patients was similar to that in patients receiving placebo. No difference was found between plasma zinc levels in a further 46 patients with idiopathic ulcerative colitis or proctitis and those obtained in a group of healthy controls.
本文报道了一项关于口服硫酸锌作为复发性特发性溃疡性结肠炎或直肠炎辅助治疗的双盲对照试验。共治疗了51名患者,接受锌治疗的患者在临床和乙状结肠镜检查方面的改善与接受安慰剂的患者相似。在另外46名特发性溃疡性结肠炎或直肠炎患者中,血浆锌水平与一组健康对照者相比未发现差异。