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透明质酸软组织填充剂治疗小颏畸形的观察研究。

Hyaluronic Acid Soft Tissue Filler for the Treatment of The Hypoplastic Chin: An Observational Study.

机构信息

Private Practice, West Palm Beach, Florida.

Watson and Stonehouse Enterprises LLC, Pacific Grove, California.

出版信息

Dermatol Surg. 2020 Aug;46(8):1092-1101. doi: 10.1097/DSS.0000000000002326.

Abstract

BACKGROUND

The hypoplastic chin is associated with facial unattractiveness.

OBJECTIVE

To evaluate safety and efficacy of JUVÉDERM Voluma XC Injectable Gel (hyaluronic acid filler, HAF) for treatment of hypoplastic chin.

METHODS

This was a one-year, open-label, single-center study.

RESULTS

Thirty subjects received HAF injections of which 24 subjects (80%) completed the study. Mean facial angle significantly improved at all time points compared with baseline, improving by 1.83° (95% confidence interval, 0.91, 2.75; p < .001) at 12 months. Subject satisfaction with lower face and jawline increased significantly for all FACE-Q questions and time points compared with baseline (p < .05). Subject satisfaction with overall facial appearance, and percentage of subjects "not bothered" by area under chin increased significantly for most FACE-Q questions and time points compared with baseline (p < .05).

CONCLUSION

In this completed one-year study, HAF injection for hypoplastic chin was safe and accompanied by significant improvement in facial angle, measures of subject satisfaction, and GAIS.

摘要

背景

小颏与面部不美观有关。

目的

评估 JUVÉDERM Voluma XC 注射凝胶(透明质酸填充物,HAF)治疗小颏畸形的安全性和有效性。

方法

这是一项为期一年的、开放性、单中心研究。

结果

30 名受试者接受了 HAF 注射,其中 24 名受试者(80%)完成了研究。与基线相比,所有时间点的面部角度均显著改善,12 个月时改善 1.83°(95%置信区间,0.91,2.75;p<.001)。与基线相比,所有 FACE-Q 问题和时间点的受试者对下面部和下颌线的满意度均显著增加(p<.05)。与基线相比,大多数 FACE-Q 问题和时间点的受试者对整体面部外观的满意度以及对颏下区域“不困扰”的百分比均显著增加(p<.05)。

结论

在这项为期一年的研究中,HAF 注射治疗小颏畸形是安全的,并伴有面部角度、受试者满意度和 GAIS 的显著改善。

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