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加拿大抗癌伙伴组织直肠癌项目:一项泛加拿大多学科质量改进倡议的方案,旨在优化直肠癌护理质量。

The Canadian Partnership Against Cancer Rectal Cancer Project: Protocol for a Pan-Canadian, Multidisciplinary Quality Improvement Initiative to Optimize the Quality of Rectal Cancer Care.

作者信息

Pooni Amandeep, Schmocker Selina, Brown Carl, MacLean Anthony, Williams Lara, Baxter Nancy N, Simunovic Marko, Liberman Alexander Sender, Drolet Sebastien, Neumann Katerina, Jhaveri Kartik, Kirsch Richard, Kennedy Erin Diane

机构信息

Department of Surgery, Mount Sinai Hospital, Toronto, ON, Canada.

Institute of Health Policy, Management, and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.

出版信息

JMIR Res Protoc. 2020 Jan 29;9(1):e15535. doi: 10.2196/15535.

Abstract

BACKGROUND

Over the last 2 decades, the use of multimodal strategies, including total mesorectal excision (TME) surgery, preoperative chemotherapy, multidisciplinary case conference, pelvic magnetic resonance imaging, and pathologic assessment using Quirke method, has led to significant improvements in oncologic outcomes for patients with rectal cancer. Although the literature supports claims on the effectiveness of these multimodal strategies, the uptake of these multimodal strategies varies considerably among centers, suggesting that the best evidence is not always implemented into clinical practice.

OBJECTIVE

This study aims to perform a quality improvement initiative to (1) identify existing gaps in care for these multimodal strategies and (2) implement knowledge translation (KT) interventions to close these gaps to optimize quality of care for patients with rectal cancer across high-volume centers in Canada.

METHODS

Process indicators for the selected multimodal strategies to optimize rectal cancer care will be selected and prospectively collected for all patients with stages 1 to 3 rectal cancer undergoing TME surgery. KT interventions, including audit and feedback, opinion leaders, and community of practice, will be implemented to increase the uptake of these clinical strategies.

RESULTS

The uptake of the process indicators over time and the effect of the uptake of the process indicators on short- and long-term oncologic outcomes will be evaluated for each multimodal strategy.

CONCLUSIONS

This quality improvement initiative will identify existing gaps in care for the selected multimodal strategies and implement KT interventions to close these gaps. The results of this study will inform further efforts to optimize rectal cancer care.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/15535.

摘要

背景

在过去20年中,多模式策略的应用,包括全直肠系膜切除术(TME)、术前化疗、多学科病例讨论、盆腔磁共振成像以及使用奎克方法进行病理评估,已使直肠癌患者的肿瘤学结局得到显著改善。尽管文献支持这些多模式策略的有效性,但这些多模式策略在各中心的采用情况差异很大,这表明最佳证据并非总能应用于临床实践。

目的

本研究旨在开展一项质量改进计划,以(1)识别这些多模式策略在护理方面存在的现有差距,以及(2)实施知识转化(KT)干预措施来弥合这些差距,从而优化加拿大各大高容量中心直肠癌患者的护理质量。

方法

将选择并前瞻性收集针对优化直肠癌护理的所选多模式策略的过程指标,用于所有接受TME手术的1至3期直肠癌患者。将实施KT干预措施,包括审核与反馈、意见领袖以及实践社区,以提高这些临床策略的采用率。

结果

将针对每种多模式策略评估过程指标随时间的采用情况以及过程指标的采用对短期和长期肿瘤学结局的影响。

结论

这项质量改进计划将识别所选多模式策略在护理方面存在的现有差距,并实施KT干预措施来弥合这些差距。本研究结果将为进一步优化直肠癌护理的努力提供参考。

国际注册报告识别码(IRRID):DERR1-10.2196/15535

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbe1/7016615/b2c32c32adf1/resprot_v9i1e15535_fig1.jpg

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