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一名老年男性肾病综合征患者的播散性诺卡菌感染

Disseminated Nocardia Infection in an Old Male Patient with Nephrotic Syndrome.

作者信息

Yang Wanchun, Zhao Lei, Tang Meng, Jiang Yinling, Zhu Ziwen, Brady Tucker J, Xiao Huaping, Bai Qian, Wakefield Mark R, Fang Yujiang

出版信息

Clin Lab. 2020 Jan 1;66(1). doi: 10.7754/Clin.Lab.2019.190638.

Abstract

BACKGROUND

Nocardia infection is a very rare bacterial infection caused by Gram-positive, aerobic nocardia species. However, in recent years, it has become a serious infection in immunocompromised patients. Earlier diagnosis plays a pivotal in the effective treatment of nocardia infection.

METHODS

In this study, we reported a 65-year-old male patient with nephrotic syndrome who had disseminated abscesses in the lungs, right lower limb, and right cheek.

RESULTS

Bacterial culture from these lesions confirmed the presence of nocardia. Timely administration of sensitive antibiotics resulted in a quick recovery for this patient.

CONCLUSIONS

Nocardia infection should be considered in the differential diagnosis of infectious lesions, especially when a patient has multiple abscesses and an underlying disorder in which the immune function of the patient may be compromised.

摘要

背景

诺卡菌感染是一种由革兰氏阳性需氧诺卡菌引起的非常罕见的细菌感染。然而,近年来,它已成为免疫功能低下患者的一种严重感染。早期诊断对诺卡菌感染的有效治疗起着关键作用。

方法

在本研究中,我们报告了一名65岁的肾病综合征男性患者,其肺部、右下肢和右脸颊出现播散性脓肿。

结果

这些病变的细菌培养证实存在诺卡菌。及时给予敏感抗生素使该患者迅速康复。

结论

在感染性病变的鉴别诊断中应考虑诺卡菌感染,尤其是当患者有多个脓肿且存在可能损害患者免疫功能的基础疾病时。

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