Maire Jenna, Galera Cédric, Bioulac Stéphanie, Bouvard Manuel, Michel Grégory
Research Unit CERES, Toulouse, France.
Department "Health and achievement in the young", INSERM U1219, University of Bordeaux, France; Child and Adolescent Psychiatry Department, Charles Perrens Hospital, Bordeaux, France.
Psychiatry Res. 2020 Jan 12;285:112789. doi: 10.1016/j.psychres.2020.112789.
Irritability and emotional lability have been shown to be severity and impairment factors in community and clinical sample studies and are frequent comorbid features of Attention Deficit Hyperactivity Disorder (ADHD). However, while irritability and emotional lability seem to be closely linked, the differential effect of these two features has received little attention. This study assessed the distinct associations of irritability and emotional lability on symptomatology in children with ADHD. One hundred and eight children diagnosed with ADHD participated in the study. Children were rated by parents on ADHD and comorbid symptomatology with the Conners Rating Scale - Revised. Irritability was the most significant predictive factor of the severity of anxiety and oppositional symptoms. Regarding emotional lability, it was significantly predictive of the severity of hyperactivity symptoms. While emotional lability shares common theoretical characteristics with irritability, each seems to be associated with specific areas. Irritability is a symptom of Oppositional Defiant Disorder, a frequent ADHD comorbidity, and also seems to be related to internalizing disorder (e.g. anxiety). Emotional lability seems to be related to ADHD severity symptoms per se. Both could be clinically informative in the diagnosis of ADHD and its comorbidities.
在社区和临床样本研究中，易怒和情绪不稳定已被证明是严重程度和损害因素，并且是注意力缺陷多动障碍（ADHD）常见的共病特征。然而，尽管易怒和情绪不稳定似乎密切相关，但这两种特征的差异影响却很少受到关注。本研究评估了易怒和情绪不稳定与ADHD儿童症状学之间的不同关联。108名被诊断为ADHD的儿童参与了该研究。父母使用修订后的康纳斯评定量表对儿童的ADHD及共病症状进行评分。易怒是焦虑和对立症状严重程度的最显著预测因素。关于情绪不稳定，它是多动症状严重程度的显著预测因素。虽然情绪不稳定与易怒具有共同的理论特征，但两者似乎都与特定领域相关。易怒是对立违抗障碍（一种常见的ADHD共病）的症状，似乎也与内化障碍（如焦虑）有关。情绪不稳定似乎本身就与ADHD严重症状有关。两者在ADHD及其共病的诊断中都可能具有临床参考价值。
