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临床质子束的横向剂量分布重建:探测器的比较。

Transversal dose profile reconstruction for clinical proton beams: A detectors inter-comparison.

机构信息

INFN-LNS, Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud, Via S. Sofia, 62, 95123 Catania, Italy.

INFN-LNS, Istituto Nazionale di Fisica Nucleare - Laboratori Nazionali del Sud, Via S. Sofia, 62, 95123 Catania, Italy.

出版信息

Phys Med. 2020 Feb;70:133-138. doi: 10.1016/j.ejmp.2020.01.006. Epub 2020 Jan 31.

Abstract

PURPOSE

The main purpose of this work is the inter-comparison between different devices devoted to the transversal dose profile recostruction for daily QA tests in proton therapy.

METHODS

The results obtained with the EBT3 radiochromic films, used as a reference, and other common quality control devices, have been compared with those obtained with a beam profiling system developed at the "Laboratori Nazionali del Sud" of Italian Institute for Nuclear Physics (INFN-LNS, Catania, Italy). It consists of a plastic scintillator screen (thickness 1 mm), mounted perpendicularly to the beam axis and coupled with a highly sensitive CCD detector in a light-tight box.

RESULTS AND CONCLUSION

The tests, carried out both at the INFN-LNS and Trento Proton Therapy Center facilities, show, in general, a good agreement between the different detectors. The beam profiling system, in particular, appears to be a promising quality control device for 2-D relative dosimetry, because of its linear response in a dose rate range useful for proton therapy treatments, its high spatial resolution and its short acquisition and processing time.

摘要

目的

本工作的主要目的是对用于质子治疗日常 QA 测试的横向剂量分布重建的不同设备进行相互比较。

方法

使用 EBT3 光致变色胶片(用作参考)和其他常见质量控制设备获得的结果与在意大利核物理研究所“南部国家实验室”(意大利卡塔尼亚,意大利)开发的束流剖面系统获得的结果进行了比较。它由一个垂直于束轴安装的塑料闪烁体屏幕(厚度 1 毫米)和一个密封在盒子中的高灵敏度 CCD 探测器组成。

结果与结论

在 INFN-LNS 和特伦托质子治疗中心设施进行的测试总体上显示出不同探测器之间的良好一致性。特别是,束流剖面系统由于其在质子治疗治疗中有用的剂量率范围内的线性响应、高空间分辨率和短采集和处理时间,似乎是一种有前途的 2-D 相对剂量测量质量控制设备。

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