Department of Surgery, Mayo Clinic, Jacksonville, FL, U.S.A.
Department of Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, U.S.A.
Anticancer Res. 2020 Feb;40(2):881-889. doi: 10.21873/anticanres.14021.
BACKGROUND/AIM: We aimed to evaluate disparities in presentation and treatment of gastric cancer (GC), including time between diagnosis and treatment, based on race, focusing on Japanese patients within the USA.
The National Cancer Database was queried for patients diagnosed with GC between 2004-2013. Clinical and treatment variables were summarized by race (White, non-Japanese Asian, Japanese). The association between race and overall survival (OS) was evaluated using the log-rank test.
A total of 79,481 patients were included. Japanese patients received surgery the earliest after diagnosis in all stages. Regarding radiotherapy, white patients had the shortest waiting time followed by Asian and Japanese patients. Asian patients had better OS at both 3 and 5 years of follow-up. White patients were associated with the lowest OS.
Japanese and Asian GC patients have better OS compared to White patients. Moreover, there were disparities in time to both GC diagnosis and treatment, with Japanese patients being sooner diagnosed and surgically treated, which may ultimately impact patient experience.
背景/目的：我们旨在评估基于种族的胃癌（GC）表现和治疗差异，包括诊断与治疗之间的时间，重点关注美国的日本患者。
国家癌症数据库被查询了 2004-2013 年间诊断为 GC 的患者。临床和治疗变量按种族（白人、非日裔亚裔、日裔）进行总结。使用对数秩检验评估种族与总生存（OS）之间的关联。
共纳入 79481 例患者。在所有阶段，日本患者在诊断后最早接受手术。在放疗方面，白人患者的等待时间最短，其次是亚裔和日本患者。在 3 年和 5 年随访时，亚裔患者的 OS 更好。白人患者的 OS 最低。
与白人患者相比，日本和亚裔 GC 患者的 OS 更好。此外，GC 诊断和治疗的时间存在差异，日本患者更早被诊断并接受手术治疗，这可能最终影响患者的体验。
