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头颈部癌症患者接受放化疗时预防性胃造口管放置和胃造口管使用的安全性。

Safety of Prophylactic Gastrostomy Tube Placement and Gastrostomy Tube Usage in Patients Treated by Radio(chemo)therapy for Head and Neck Cancer.

机构信息

Department of Otolaryngology, Head and Neck Surgery, University Hospital Marburg, Philipps-University Marburg, Marburg, Germany.

Department of Otolaryngology, Head and Neck Surgery, University of Ulm, Ulm, Germany.

出版信息

Anticancer Res. 2020 Feb;40(2):1167-1173. doi: 10.21873/anticanres.14059.

Abstract

BACKGROUND

A gastrostomy feeding tube is one method for long-term feeding support in patients undergoing radio(chemo)therapy for head and neck cancer (HNC). The aim of this study was to analyze the safety of prophylactic gastrostomy tube placement and usage in HNSCC patients.

PATIENTS AND METHODS

HNC patients undergoing percutaneous endoscopic gastrostomy (PEG) or radiological percutaneous gastrostomy (RPG) tube placement prior to radio(chemo)therapy from 2010-2014 were retrospectively reviewed regarding procedural and long-term gastrostomy tube-related complications, usage of PEG/RPG, weight profile, pretreatment and posttreatment body mass index.

RESULTS

A total of 212 patients underwent prophylactic feeding tube placement (71% RPG, 27% PEG and 2% surgical jejunostomy). A total of 173 patients utilized their gastrostomy tubes for either total or supplemental nutrition support. Despite this, 157 patients (74%) lost weight during therapy (mean weight loss=8 kg). The rate of severe tube-related complications (peritonitis/incorrect placement) was low and similar in both groups (PEG 2.7% vs. RPG 3.4%).

CONCLUSION

Although a very high proportion of patients used their PEG/RPG during radio(chemo)therapy there was a high mean weight loss. Serious complications of tube placement were rare.

摘要

背景

胃造口管是头颈部癌症(HNC)患者接受放化疗时进行长期喂养支持的一种方法。本研究旨在分析预防性胃造口管置管术在 HNSCC 患者中的安全性。

患者和方法

回顾性分析了 2010 年至 2014 年期间接受经皮内镜胃造口术(PEG)或放射性经皮胃造口术(RPG)置管术的 HNC 患者,评估了置管术和长期胃造口管相关并发症、PEG/RPG 的使用情况、体重状况、治疗前和治疗后体重指数。

结果

共 212 例患者行预防性喂养管置管术(71%为 RPG,27%为 PEG,2%为手术空肠造口术)。共有 173 例患者使用胃造口管进行全胃肠外或补充营养支持。尽管如此,157 例患者(74%)在治疗期间体重下降(平均体重减轻 8kg)。严重的与管相关的并发症(腹膜炎/置管不当)发生率在两组之间相似(PEG 为 2.7%,RPG 为 3.4%)。

结论

尽管在放化疗期间,PEG/RPG 的使用率非常高,但患者的平均体重减轻幅度较大。置管术的严重并发症罕见。

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