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Refractory Takayasu arteritis responding to the oral Janus kinase inhibitor, tofacitinib.

作者信息

Yamamura Yuriko, Matsumoto Yoshinori, Asano Yosuke, Katayama Yu, Hayashi Keigo, Ohashi Keiji, Morishita Michiko, Watanabe Haruki, Takano-Narazaki Mariko, Sada Ken-Ei, Wada Jun

机构信息

Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

出版信息

Rheumatol Adv Pract. 2019 Dec 23;4(1):rkz050. doi: 10.1093/rap/rkz050. eCollection 2020.

DOI:10.1093/rap/rkz050
PMID:32016168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6991178/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0eb/6991178/fa9eef1f72e1/rkz050f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0eb/6991178/fa9eef1f72e1/rkz050f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0eb/6991178/fa9eef1f72e1/rkz050f1.jpg

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Pathogenesis and Treatment of T-Large Granular Lymphocytic Leukemia (T-LGLL) in the Setting of Rheumatic Disease.

本文引用的文献

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Inhibition of JAK-STAT Signaling Suppresses Pathogenic Immune Responses in Medium and Large Vessel Vasculitis.JAK-STAT 信号抑制在大中血管血管炎中的致病性免疫反应。
Circulation. 2018 May 1;137(18):1934-1948. doi: 10.1161/CIRCULATIONAHA.117.030423. Epub 2017 Dec 18.
2
Efficacy and safety of tocilizumab in patients with refractory Takayasu arteritis: results from a randomised, double-blind, placebo-controlled, phase 3 trial in Japan (the TAKT study).托珠单抗治疗难治性大动脉炎的疗效和安全性:来自日本一项随机、双盲、安慰剂对照、3 期临床试验(TAKT 研究)的结果。
Ann Rheum Dis. 2018 Mar;77(3):348-354. doi: 10.1136/annrheumdis-2017-211878. Epub 2017 Nov 30.
3
风湿性疾病背景下T大颗粒淋巴细胞白血病(T-LGLL)的发病机制与治疗
Front Oncol. 2022 Jun 7;12:854499. doi: 10.3389/fonc.2022.854499. eCollection 2022.
4
An Update on Childhood-Onset Takayasu Arteritis.儿童期发病的大动脉炎最新进展
Front Pediatr. 2022 Apr 13;10:872313. doi: 10.3389/fped.2022.872313. eCollection 2022.
5
A systematic review of clinical and preclinical evidences for Janus kinase inhibitors in large vessel vasculitis.对Janus激酶抑制剂治疗大血管血管炎的临床和临床前证据的系统评价。
Clin Rheumatol. 2022 Jan;41(1):33-44. doi: 10.1007/s10067-021-05973-4. Epub 2021 Nov 3.
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Wind of Change in the Treatment of Childhood-Onset Takayasu Arteritis: a Systematic Review.儿童发病型大动脉炎治疗的变革之风:系统评价。
Curr Rheumatol Rep. 2021 Jul 3;23(8):68. doi: 10.1007/s11926-021-01032-8.
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Contribution of Janus-Kinase/Signal Transduction Activator of Transcription Pathway in the Pathogenesis of Vasculitis: A Possible Treatment Target in the Upcoming Future.Janus激酶/信号转导和转录激活因子通路在血管炎发病机制中的作用:未来可能的治疗靶点
Front Pharmacol. 2021 Mar 29;12:635663. doi: 10.3389/fphar.2021.635663. eCollection 2021.
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Curr Rheumatol Rep. 2020 Oct 12;22(12):85. doi: 10.1007/s11926-020-00961-0.
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Rheumatology (Oxford). 2020 Nov 1;59(11):e95-e98. doi: 10.1093/rheumatology/keaa281.
Phase II study of tofacitinib (CP-690,550) combined with methotrexate in patients with rheumatoid arthritis and an inadequate response to methotrexate.
托法替布(CP-690,550)联合甲氨蝶呤治疗甲氨蝶呤应答不足的类风湿关节炎的 II 期研究。
Arthritis Care Res (Hoboken). 2011 Aug;63(8):1150-8. doi: 10.1002/acr.20494.
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Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis.JAK1/JAK3 抑制剂 CP-690,550 在大鼠佐剂性关节炎中介导的抗炎活性和中性粒细胞减少作用。
J Inflamm (Lond). 2010 Aug 11;7:41. doi: 10.1186/1476-9255-7-41.
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Medium- and large-vessel vasculitis.中、大血管血管炎。
N Engl J Med. 2003 Jul 10;349(2):160-9. doi: 10.1056/NEJMra022694.
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Circulation. 1994 Oct;90(4):1855-60. doi: 10.1161/01.cir.90.4.1855.