具有聚集诱导发光特性的高效光敏剂用于溶酶体和革兰氏阳性菌靶向光动力治疗。
Efficient photosensitizers with aggregation-induced emission characteristics for lysosome- and Gram-positive bacteria-targeted photodynamic therapy.
机构信息
Key Laboratory of Macromolecular Science of Shaanxi Province, Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, School of Chemistry & Chemical Engineering, Shaanxi Normal University, 710119 Xi'an, China.
出版信息
Chem Commun (Camb). 2020 Feb 27;56(17):2630-2633. doi: 10.1039/d0cc00394h.
Two efficient photosensitizers (PSs) with aggregation-induced emission characteristics were designed and synthesized for specific lysosome-targeted photodynamic therapy (PDT). Both PSs efficiently discriminated Gram-positive bacteria from Gram-negative bacteria and killed Gram-positive bacteria through the PDT effect.
两种具有聚集诱导发光特性的高效光敏剂（PSs）被设计和合成，用于特定的溶酶体靶向光动力疗法（PDT）。这两种 PSs 都能有效地区分革兰氏阳性菌和革兰氏阴性菌，并通过 PDT 效应杀死革兰氏阳性菌。
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