Miersch W D
Department of Urology, University of Bonn, FRG.
Urol Int. 1988;43(5):269-71. doi: 10.1159/000281352.
A new rat model is presented to study the carcinogenesis in colonic urinary diversion. Surgical techniques performed on humans are simulated by microsurgery. The altered metabolism--hyperchloraemic acidosis--is taken into consideration. It seems to be an important co-factor for the carcinogenesis.
提出了一种新的大鼠模型来研究结肠尿流改道中的致癌作用。通过显微手术模拟人类实施的手术技术。考虑到代谢改变——高氯性酸中毒。它似乎是致癌作用的一个重要辅助因素。