Mother-Child, Urological Science Department, Sapienza University, Rome, Italy.
Pediatr Allergy Immunol. 2020 Feb;31 Suppl 24:32-33. doi: 10.1111/pai.13164.
Rhinitis is a common, under-diagnosed condition in childhood and adolescence. Pathogenic classification of rhinitis includes allergic rhinitis (AR) and non-allergic rhinitis (NAR); the latter is characterized by non-infectious and infectious subtypes; non-infectious subtype is by far the most prevalent in infancy. Endotyping may help to predict chronic rhinosinusitis (CRS) risk factors, as well as disease progression and response to different treatments. The validation of pediatric algorithms and the implementation of novel biotherapeutics in the endotype-driven integrated pathways of CRS will lead in the next future to more successful disease management.
鼻炎是儿童和青少年期常见的、诊断不足的疾病。鼻炎的病原学分类包括过敏性鼻炎（AR）和非过敏性鼻炎（NAR）；后者以非传染性和传染性亚型为特征；非传染性亚型在婴儿期最为常见。表型分类可能有助于预测慢性鼻-鼻窦炎（CRS）的危险因素，以及疾病的进展和对不同治疗的反应。在 CRS 的表型驱动综合途径中，儿科算法的验证和新型生物疗法的实施将在未来带来更成功的疾病管理。
