Baron Samuel L, Klein David S, Frank Rachel M, Rodeo Scott, Vangsness Thomas, Jazrawi Laith M
Instr Course Lect. 2020;69:661-670.
Orthobiologics continue to be one of the most discussed and trending topics in orthopaedic surgery today. Pathology of tendons, ligaments, bone, cartilage, and meniscal tissue are all theoretically treatable with biologics. Ultimately, the hope for biologics is to provide symptom relief and improve tissue healing with the potential to treat some conditions without the need for surgery. It is important to review the current state of biologic therapies available for musculoskeletal disease, discuss government regulations and barriers to use, and, finally, examine current research in biologics and what the future may hold.
目前,骨科生物制剂仍然是最受关注且热度最高的话题之一。从理论上讲,肌腱、韧带、骨骼、软骨和半月板组织的病变都可以用生物制剂进行治疗。生物制剂的最终目标是缓解症状、促进组织愈合,并有可能在无需手术的情况下治疗某些疾病。回顾用于肌肉骨骼疾病的生物治疗方法的现状、讨论政府法规及使用障碍,最后研究生物制剂的当前研究情况以及未来发展前景,这非常重要。