Department of Reproductive Endocrinology and Infertility, Sisli Kolan International Hospital, Istanbul, Turkey.
Bandirma Onyedi Eylül University, Faculty of Health Sciences, Balıkesir, Turkey.
J Gynecol Obstet Hum Reprod. 2020 Apr;49(4):101707. doi: 10.1016/j.jogoh.2020.101707. Epub 2020 Feb 1.
To compare the clinical pregnancy and live birth results of fresh embryo transfer (ET) and selective frozen embryo transfer (sFET) in cohort of infertile patients aged between 18-42 years of age in single IVF center.
In this retrospective cross-sectional study, the clinical and live birth results of 620 fresh embryo transfer cycles and 580 frozen embryo transfer cycles were investigated in Sisli Kolan International Hospital Fertility Unit between 2015-2018.
Age, BMI, causes of infertility, duration of infertility, ovulation induction protocols, the number of oocytes collected and the thickness of endometrium on the day of transfer were similar in the ET and sFET groups. More good quality embryos were obtained in sFET group. The clinical pregnancy and live birth rates were 71.04 % and 59.31 % in the sFET groups, and 56.77 % and 44.52 % in the ET group, respectively (p < 0.05).
Pregnancy, clinical pregnancy and live birth rates were higher in frozen embryo transfer cycles than in fresh embryo cycles. However, appropriate in vitro fertilization and embryo transfer methods suitable for each patient should be determined before choosing fresh ET or sFET treatment modalities.
比较在单中心内年龄为 18-42 岁的不孕患者队列中新鲜胚胎移植（ET）和选择性冷冻胚胎移植（sFET）的临床妊娠和活产结局。
本回顾性横断面研究调查了 2015 年至 2018 年 Sisli Kolan 国际医院生殖单位的 620 个新鲜胚胎移植周期和 580 个冷冻胚胎移植周期的临床和活产结局。
ET 组和 sFET 组的年龄、BMI、不孕原因、不孕持续时间、排卵诱导方案、获卵数和移植日子宫内膜厚度相似。sFET 组获得更多的优质胚胎。sFET 组的临床妊娠率和活产率分别为 71.04%和 59.31%，而 ET 组分别为 56.77%和 44.52%（p<0.05）。
冷冻胚胎移植周期的妊娠率、临床妊娠率和活产率均高于新鲜胚胎移植周期。然而，在选择新鲜 ET 或 sFET 治疗方式之前，应确定适合每个患者的适当体外受精和胚胎移植方法。
