Frieling T, Enck P, Bremer G, Lübke H J, Berges W, Wienbeck M
Universität Düsseldorf, Medizinische Klinik.
Z Gastroenterol. 1988 Nov;26(11):689-93.
We prospectively compared esophageal and rectal motility data from 7 patients with progressive systemic sclerosis (4 females, 3 males) to esophageal recordings in 22 and anorectal recordings in 9 healthy controls. All patients with sclerosis exhibited motility disturbances in the lower esophageal sphincter (LES): LES resting pressure, LES relaxation amplitude and duration, and the number of incomplete LES relaxations were significantly different compared to the controls. All patients had alterations of anorectal motility: resting pressure, maximal squeeze pressure, and sphincter relaxation amplitude following balloon distension of the rectum were significantly decreased as compared to the control subjects. We conclude that esophageal and anorectal manometry are comparable in their sensitivity to differentiate between patients with systemic sclerosis and normal subjects.
我们前瞻性地比较了7例进行性系统性硬化症患者(4名女性,3名男性)的食管和直肠动力数据,以及22名健康对照者的食管记录和9名健康对照者的肛门直肠记录。所有硬化症患者的食管下括约肌(LES)均表现出动力障碍:与对照组相比,LES静息压、LES松弛幅度和持续时间以及LES不完全松弛次数均有显著差异。所有患者均有肛门直肠动力改变:与对照组相比,直肠球囊扩张后的静息压、最大挤压压力和括约肌松弛幅度均显著降低。我们得出结论,食管和肛门直肠测压在区分系统性硬化症患者和正常受试者方面的敏感性相当。