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[进行性系统性硬化症食管受累的临床与测压相关性]

[Clinico-manometric correlation in esophageal involvement of progressive systemic sclerosis].

作者信息

Corti R E, Outeda J L, Naveiro J J, Nicolino D, Corti R N, Crosetti E

出版信息

Acta Gastroenterol Latinoam. 1982;12(1):1-9.

PMID:7136451
Abstract

The esophageal response studied in the systemic illness has been developed clearly in the body of the esophagus as well as in the lower esophageal sphincter, showing important alterations in the peristalsis and a significant fall of lower esophageal sphincter pressure, proving conditions such as those in which gastro-esophageal reflux is produced. The authors studied the esophageal motility in 10 patients with progressive systemic sclerosis by electromanometry by means of an open-tipped catheters system. They found that the pressure of the inferior esophageal sphincter was altered in the 100 per cent of the cases; in 50% of the patients there was a lack of peristaltic waves and in the remaining 50% the middle pressure was less than in normal subjects. It was observed dysquinethic waves in 40% of the cases. The intensity of the epidermic compromise is no related with alterations in the esophageal functioning.

摘要

在全身性疾病中所研究的食管反应,已在食管体部以及食管下括约肌中明确显现,表现为蠕动的重要改变以及食管下括约肌压力显著下降,证实了诸如产生胃食管反流的那些情况。作者通过使用开放尖端导管系统的食管测压法,对10例进行性系统性硬化症患者的食管动力进行了研究。他们发现,100%的病例中食管下括约肌压力发生改变;50%的患者缺乏蠕动波,其余50%患者的平均压力低于正常受试者。在40%的病例中观察到了不协调波。表皮损伤的严重程度与食管功能改变无关。

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