Huo Hangfeng, Seger Carol A, Zhou Dandan, Chen Zhiyi, Xu Ting, Zhang Rong, Feng Tingyong, Chen Qi
School of Psychology, South China Normal University, 510631 Guangzhou, China; Center for Studies of Psychological Application, South China Normal University, 510631 Guangzhou, China; Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, 510631 Guangzhou, China.
School of Psychology, South China Normal University, 510631 Guangzhou, China; Center for Studies of Psychological Application, South China Normal University, 510631 Guangzhou, China; Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, 510631 Guangzhou, China; Department of Psychology and Program in Molecular, Cellular, and Integrative Neurosciences, Colorado State University, Fort Collins, CO 80523, USA.
Brain Cogn. 2020 Apr;140:105533. doi: 10.1016/j.bandc.2020.105533. Epub 2020 Feb 1.
We used voxel-based morphometry and resting-state functional magnetic resonance imaging (rs-fMRI) to investigate whether the regulatory mode orientation of assessment (the tendency of each individual to self-regulate by critically evaluating alternatives) interacts with neural systems underlying risk-taking. Across a sample of 112 participants, propensity for risk-taking (measured using the Wheel of Fortune task) was negatively correlated with assessment orientation, such that a greater tendency to critically evaluate alternatives was associated with a lower tendency for risk-taking. VBM revealed a negative correlation between assessment orientation and right inferior parietal lobe (RIPL) gray matter volume. Resting-state functional connectivity (rs-FC) between this same RIPL region and the left inferior frontal gyrus (LIFG) was positively correlated with assessment orientation in an independent sample of 41 participants. Most importantly, based on the rs-FC results, a mediation analysis indicated that assessment orientation played a completely mediating role in the relation between the functional connectivity of RIPL-LIFG and risk-taking. These results suggest that assessment orientation may affect risk-taking via the RIPL and its connectivity with LIFG. On the whole, the present study yields the insights into how the assessment dimension of regulatory mode affects risk-taking, and provides a novel account of the neural substrate of this relationship.
我们使用基于体素的形态测量法和静息态功能磁共振成像（rs-fMRI）来研究评估的调节模式取向（即个体通过批判性评估备选方案进行自我调节的倾向）是否与冒险行为背后的神经系统相互作用。在112名参与者的样本中，冒险倾向（使用幸运轮任务进行测量）与评估取向呈负相关，即批判性评估备选方案的倾向越强，冒险倾向越低。基于体素的形态测量法显示，评估取向与右下顶叶（RIPL）灰质体积呈负相关。在41名参与者的独立样本中，同一RIPL区域与左下额回（LIFG）之间的静息态功能连接（rs-FC）与评估取向呈正相关。最重要的是，基于rs-FC结果的中介分析表明，评估取向在RIPL-LIFG功能连接与冒险行为之间的关系中起完全中介作用。这些结果表明，评估取向可能通过RIPL及其与LIFG的连接来影响冒险行为。总体而言，本研究揭示了调节模式的评估维度如何影响冒险行为，并为这种关系的神经基础提供了新的解释。
