Katenkamp D, Kosmehl H, Langbein L
Institut für Pathologie, Friedrich-Schiller-Universität Jena, DDR.
Zentralbl Allg Pathol. 1988;134(4-5):423-33.
An analysis was made of 229 cases of angiomyoma retrieved from the authors' own files. Studies were aimed at histological features, morphological variability, tumour localisation as well as at distribution by sexes and age groups. The angiomyoma cases were subdivided by histological features into solid forms (18 per cent), venous forms (38 per cent), combinations (43 per cent), and cavernous variants (two cases only). That subdivision was based on variable relationships between smooth muscles, on the one hand, and vascular cavities of different shapes, on the other. Angiomyoma was found to occur in high incidence in the fourth to sixth decennium of age, with clearly recordable predilection for females, and localized in 40 per cent of all cases in the region of the lower leg. Noteworthy peculiarities included predominance of male patients with combined or mixed angiomyoma with cavernous components or with solely cavernous forms and preference of the venous subtype for the head-neck region. The morphological structure of angiomyoma is discussed in some detail and is interpreted as a correlate of an organoid mixed tumour with muscular and vascular components. It is against this background that the term of "angiomyoma" is definitely preferred to "vascular leiomyoma".
对作者自有档案中检索出的229例血管肌瘤病例进行了分析。研究旨在了解其组织学特征、形态变异性、肿瘤定位以及性别和年龄组分布情况。血管肌瘤病例根据组织学特征分为实体型(18%)、静脉型(38%)、混合型(43%)和海绵状变型(仅2例)。这种分类基于一方面平滑肌与另一方面不同形状血管腔之间的可变关系。血管肌瘤在40至60岁年龄段高发,明显多见于女性,40%的病例位于小腿区域。值得注意的特点包括,患有合并或混合性血管肌瘤且有海绵状成分或仅为海绵状型的男性患者占优势,以及静脉亚型在头颈部区域更为常见。文中详细讨论了血管肌瘤的形态结构,并将其解释为具有肌肉和血管成分的类器官混合瘤的一种相关表现。正是在此背景下,“血管肌瘤”这一术语绝对比“血管平滑肌瘤”更可取。