Protzel C, Hakenberg O W
Helios Kliniken Schwerin, Wismarsche Straße 393-397, 19049, Schwerin, Deutschland.
Klinik und Poliklinik für Urologie, Universitätsmedizin Rostock, Rostock, Deutschland.
Urologe A. 2020 Feb;59(2):209-218. doi: 10.1007/s00120-020-01128-6.
The incidence of penile cancer in central Europe and North America is low, and patients often present at a late stage of the disease. The diagnosis can very often be made by visual examination of the primary tumor. Its morphology, size, and location as well as the inguinal lymph nodes are of clinical interest. The removal of (micro)metastatic lymph nodes is decisive for the prognosis. These cannot be diagnosed clinically or by imaging with sufficient reliability, which makes invasive lymph node staging necessary. Penile cancer can only be cured by surgery in patients with localized cancer and early stage regional lymph node metastasis. The primary tumor, including metastatic lymph nodes, must be completely excised as early as possible. If indicated, organ preservation must be performed with strict adherence of safety margins. Optimal lymph node management is crucial for long-term survival.
中欧和北美的阴茎癌发病率较低,患者常于疾病晚期就诊。通常可通过对原发肿瘤进行视诊来做出诊断。其形态、大小、位置以及腹股沟淋巴结具有临床意义。(微)转移淋巴结的切除对预后起决定性作用。这些无法通过临床检查或影像学检查可靠地诊断出来,这使得有创性淋巴结分期成为必要。阴茎癌仅在局部癌症和早期区域淋巴结转移的患者中可通过手术治愈。必须尽早完整切除原发肿瘤,包括转移淋巴结。如有必要,进行器官保留时必须严格遵守安全切缘。优化的淋巴结处理对长期生存至关重要。