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终末期感染性全膝关节置换失败后单平面与双平面单侧外固定器膝关节融合术的比较研究

Uniplanar versus biplanar monolateral external fixator knee arthrodesis after end-stage failed infected total knee arthroplasty: a comparative study.

作者信息

Corona Pablo S, Jurado Maria, Scott-Tennent Ana, Fraile Rosa, Carrera Luis, Vicente Matías

机构信息

Septic and Reconstructive Surgery Unit, Orthopaedic Surgery Department, Vall D'Hebron University Hospital, Universitat Autónoma de Barcelona, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain.

Septic and Reconstructive Surgery Unit, Orthopaedic Surgery Department, Vall D'Hebron University, Barcelona, Spain.

出版信息

Eur J Orthop Surg Traumatol. 2020 Jul;30(5):815-825. doi: 10.1007/s00590-020-02633-2. Epub 2020 Feb 4.

Abstract

BACKGROUND

External fixator knee arthrodesis is a salvage procedure used primarily in cases of end-stage infected total knee replacement (iTKR). Stable fixation combined with bone-end compression is essential to achieve knee fusion, but providing sufficient stability can be challenging in the presence of severe bone loss. Our hypothesis is that using an external fixation biplanar configuration would bring about a fusion rate superior to that of a monolateral frame.

METHODS

This study compares outcomes of biplanar external fixator knee fusion due to non-revisable iTKR with those of a historical cohort control study with patients managed with a monoplanar configuration. Primary endpoints were fusion rate, time to achieve bone fusion and infection eradication rate. Limb-length discrepancy, pain level, patient satisfaction and health-related quality of life were evaluated.

RESULTS

A total of 29 knee fusion cases were included. In the biplanar group, infection was eradicated in 100% of the patients and fusion was achieved in all cases within an average of 5.24 months. In comparison, in the monolateral group, infection was eradicated in 86% of the cases and fusion was achieved in 81% of the patients after a mean of 10.3 months (p < 0.05). In both groups, postoperative pain was mild and patients expressed a high degree of satisfaction once fusion was achieved.

CONCLUSIONS

According to our data, external fixation knee fusion is a useful limb-salvage procedure in end-stage cases of knee PJI. We conclude that a biplanar configuration can halve the time required to achieve solid bone fusion in such a complex scenario.

摘要

背景

外固定器膝关节融合术是一种挽救性手术,主要用于终末期感染性全膝关节置换(iTKR)病例。稳定的固定结合骨端加压对于实现膝关节融合至关重要,但在存在严重骨丢失的情况下提供足够的稳定性可能具有挑战性。我们的假设是,使用双平面外固定构型将带来优于单侧框架的融合率。

方法

本研究比较了因不可翻修的iTKR行双平面外固定器膝关节融合术的结果与历史队列对照研究中采用单平面构型治疗的患者的结果。主要终点是融合率、实现骨融合的时间和感染根除率。评估肢体长度差异、疼痛程度、患者满意度和与健康相关的生活质量。

结果

共纳入29例膝关节融合病例。在双平面组中,100%的患者感染得到根除,所有病例平均在5.24个月内实现融合。相比之下,在单平面组中,86%的病例感染得到根除,81%的患者在平均10.3个月后实现融合(p<0.05)。两组术后疼痛均较轻,融合实现后患者均表示高度满意。

结论

根据我们的数据,外固定膝关节融合术在膝关节PJI的终末期病例中是一种有用的肢体挽救手术。我们得出结论,在这种复杂情况下,双平面构型可将实现坚实骨融合所需的时间减半。

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