功能磁共振成像作为评估肾脏疾病间质纤维化和预后的工具
Functional MRI as a Tool for Evaluating Interstitial Fibrosis and Prognosis in Kidney Disease.
作者信息
Zhang Jiong, Zhang Long Jiang
机构信息
National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
出版信息
Kidney Dis (Basel). 2020 Jan;6(1):7-12. doi: 10.1159/000504708. Epub 2019 Dec 3.
Abstract
BACKGROUND
Kidney fibrosis is a key driver of progression of kidney diseases. Renal biopsies remain the gold-standard approach to specifically diagnose and stage renal fibrosis at present. However, there is a lack of multi-dimensional pictures showing renal function, histology, and imaging of the fibrotic kidney.
SUMMARY
Magnetic resonance imaging (MRI) strategies have been rapidly evolving during the past couple of decades, especially driven by advances in technology. Recently, several pioneer and remarkable studies demonstrated that advanced functional MRI (fMRI) tools could be useful for the evaluation of kidney fibrosis and progression, which provides more opportunities to benefit from the significant value of fMRI tools for clinical implementation.
KEY MESSAGES
fMRI will be a novel approach to evaluate interstitial fibrosis and prognosis in kidney disease.
摘要
背景
肾纤维化是肾脏疾病进展的关键驱动因素。肾活检仍是目前特异性诊断和分期肾纤维化的金标准方法。然而，缺乏显示纤维化肾脏的肾功能、组织学和影像学的多维度图像。
总结
在过去几十年中，磁共振成像（MRI）技术迅速发展，特别是在技术进步的推动下。最近，几项开创性的重要研究表明，先进的功能磁共振成像（fMRI）工具可用于评估肾纤维化及其进展，这为临床应用中受益于fMRI工具的显著价值提供了更多机会。
关键信息
fMRI将成为评估肾脏疾病间质纤维化和预后的一种新方法。
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