Department of Genetics, Perelman School of Medicine, University of Pennsylvania.
Wellcome Sanger Institute, Hinxton, United Kingdom.
Genome Biol Evol. 2020 Apr 1;12(4):407-412. doi: 10.1093/gbe/evaa019.
Baboons are one of the most abundant large nonhuman primates and are widely studied in biomedical, behavioral, and anthropological research. Despite this, our knowledge of their evolutionary and demographic history remains incomplete. Here, we report a 0.9-fold coverage genome sequence from a 5800-year-old baboon from the site of Ha Makotoko in Lesotho. The ancient baboon is closely related to present-day Papio ursinus individuals from southern Africa-indicating a high degree of continuity in the southern African baboon population. This level of population continuity is rare in recent human populations but may provide a good model for the evolution of Homo and other large primates over similar timespans in structured populations throughout Africa.
狒狒是最丰富的大型非人类灵长类动物之一，广泛应用于生物医学、行为和人类学研究。尽管如此，我们对其进化和人口历史的了解仍然不完整。在这里，我们报告了来自莱索托哈马科托科遗址的一只 5800 岁狒狒的基因组序列，覆盖率为 0.9 倍。这只古老的狒狒与现今生活在南非的南方白眉猴个体密切相关，这表明在整个非洲，南部非洲狒狒种群具有高度的连续性。这种人口连续性在现代人类中很少见，但可能为人类和其他大型灵长类动物在非洲各地结构人口中类似时间段的进化提供了一个很好的模型。
