Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Sci Adv. 2019 Jan 30;5(1):eaau6947. doi: 10.1126/sciadv.aau6947. eCollection 2019 Jan.
Recent studies suggest that closely related species can accumulate substantial genetic and phenotypic differences despite ongoing gene flow, thus challenging traditional ideas regarding the genetics of speciation. Baboons (genus ) are Old World monkeys consisting of six readily distinguishable species. Baboon species hybridize in the wild, and prior data imply a complex history of differentiation and introgression. We produced a reference genome assembly for the olive baboon () and whole-genome sequence data for all six extant species. We document multiple episodes of admixture and introgression during the radiation of baboons, thus demonstrating their value as a model of complex evolutionary divergence, hybridization, and reticulation. These results help inform our understanding of similar cases, including modern humans, Neanderthals, Denisovans, and other ancient hominins.
最近的研究表明，尽管存在持续的基因流，密切相关的物种仍可以积累大量的遗传和表型差异，从而挑战了关于物种形成遗传学的传统观念。狒狒（属）是旧世界猴的一种，由六个易于区分的物种组成。狒狒物种在野外杂交，先前的数据表明它们存在着复杂的分化和基因渗入历史。我们为橄榄狒狒（）生成了参考基因组组装，为所有六种现存物种生成了全基因组序列数据。我们记录了狒狒辐射过程中的多次混合和基因渗入事件，从而证明了它们作为复杂进化分歧、杂交和网状进化模型的价值。这些结果有助于我们理解类似的情况，包括现代人类、尼安德特人、丹尼索瓦人和其他古代人类。
