Goldust Mohamad, Rahmatpour Rokni Ghasem, Weinberg Jeffrey M., Kircik Leon, Bagot Martine
J Drugs Dermatol. 2020 Jan 1;19(1):92-94. doi: 10.36849/JDD.2020.4675.
Necrobiosis lipoidica (NL) and sarcoidosis are granulomatous disorders with an unknown pathogenesis. They may coexist in the same patient, which suggests a possible overlap between these diseases among shared granulomatous inflammatory pathways. Case Presentation: This study presents the case of a non-diabetic 52-year-old woman who presented with red-yellowish border plaques on the face and upper extremities previously diagnosed as sarcoidosis. After 13 years of inappropriate treatment, histopathological findings consistent with the clinical and para-clinical examination suggested the diagnosis of NL. After treatment with an intralesional injection of steroids, significant improvement was observed, and no recurrent lesions were found. CONCLUSION: Necrobiosis lipoidica may mimic cutaneous sarcoidosis. Prompt recognition and treatment of NL can be helpful for managing the disease. J Drugs Dermatol. 2020;19(1):92-94. doi:10.36849/JDD.2020.4675
类脂质渐进性坏死（NL）和结节病是发病机制不明的肉芽肿性疾病。它们可能在同一患者中共存，这表明在这些疾病之间的共享肉芽肿性炎症途径中可能存在重叠。病例报告：本研究报告了一例52岁非糖尿病女性患者的病例，该患者面部和上肢出现红黄边界斑块，此前被诊断为结节病。经过13年的不恰当治疗后，组织病理学检查结果与临床及辅助检查结果一致，提示诊断为NL。经皮损内注射类固醇治疗后，观察到明显改善，且未发现复发病变。结论：类脂质渐进性坏死可能模仿皮肤结节病。及时识别和治疗NL有助于疾病的管理。《药物皮肤病学杂志》。2020年；19（1）：92 - 94。doi:10.36849/JDD.2020.4675
