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美国不同年龄组涉及酒精致机动车事故的患者及其相关临床结局的种族和民族差异

Racial and ethnic differences in patients involved in alcohol-impaired motor vehicle crashes and its related clinical outcomes among various age groups in the U.S.

机构信息

College of Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, California.

David Geffen School of Medicine, UCLA, Los Angeles, California.

出版信息

Traffic Inj Prev. 2020;21(2):115-121. doi: 10.1080/15389588.2019.1688312. Epub 2020 Feb 5.

DOI:10.1080/15389588.2019.1688312
PMID:32023129
Abstract
  1. to determine whether the proportion of alcohol-impaired patients involved in motor vehicle crashes (MVCs) varies by race/ethnicity within different age groups; 2) to explore the relationship between alcohol impairment, race/ethnicity and clinical outcomes among patients involved in MVCs across age groups. The 2012 National Trauma Data Bank (NTDB) queried for patients aged 16-55 involved in MVCs who received a blood ethanol test on admission. Of the 44,216 patients involved in MVC, 68% were White, 14% Black, and 13% were Hispanic. About 36% were 16-25years old, and 19% were 46-55years old. Alcohol-impaired patients constituted 34% of the patients. The multiple logistic regression analysis of HLOS ≥ 2days revealed that, when controlling for age, gender, race/ethnicity, insurance status, and the interaction between alcohol impairment and age as well as alcohol impairment and race/ethnicity, alcohol impairment positivity carried a 15% increase in probability of HLOS ≥ 2days (OR 1.15, p<0.0001). Additionally, using the 16-25 age group as reference, each of the older age groupings showed an increased probability of HLOS ≥ 2days with ORs of 1.15, 1.32, and 1.51 for ages 26-35, 36-45, and 46-55, respectively (p-values<0.0001). Blacks, Hispanics, and Asians/others were less likely than Whites to have HLOS ≥ 2days with OR of 0.88, 0.89, and 0.88, respectively (p<0.05). There was no statistically significant difference in the clinical outcome of mortality between races/ethnicities and alcohol-impaired driving. This study demonstrates that the proportions of alcohol-impaired driving and the associated clinical outcomes vary among race/ethnic groups in different age groups. More research is needed to determine the reasons for the observed differences in these vulnerable sub-groups.
摘要

1)确定在不同年龄组内,涉及机动车事故(MVC)的酒精中毒患者比例是否因种族/民族而异;2)探讨不同年龄组内涉及 MVC 的患者中酒精中毒、种族/民族与临床结局之间的关系。2012 年国家创伤数据库(NTDB)查询了年龄在 16-55 岁之间、入院时接受血液乙醇测试的 MVC 患者。在 44216 名涉及 MVC 的患者中,68%为白人,14%为黑人,13%为西班牙裔。约 36%为 16-25 岁,19%为 46-55 岁。酒精中毒患者占患者总数的 34%。多因素逻辑回归分析显示,HLOS ≥ 2 天与年龄、性别、种族/民族、保险状况以及酒精中毒与年龄和酒精中毒与种族/民族之间的相互作用有关,当控制这些因素后,酒精中毒阳性患者 HLOS ≥ 2 天的概率增加了 15%(OR 1.15,p<0.0001)。此外,以 16-25 岁年龄组为参照,每个年龄组的 HLOS ≥ 2 天的概率都有所增加,OR 分别为 1.15、1.32 和 1.51,年龄分别为 26-35 岁、36-45 岁和 46-55 岁(p 值均<0.0001)。黑人、西班牙裔和亚洲/其他族裔的 HLOS ≥ 2 天的可能性均低于白人,OR 分别为 0.88、0.89 和 0.88(p<0.05)。不同种族/民族之间的死亡率在临床结局上无统计学差异。本研究表明,在不同年龄组内,酒精中毒驾驶的比例及其相关的临床结局因种族/民族而异。需要进一步研究确定这些弱势群体中观察到的差异的原因。

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