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15克D-木糖吸收试验：其在乳糜泻研究中的应用。

The 15 g D-xylose absorption test: its application to the study of coeliac disease.

作者信息

Stevens F M, Watt D W, Bourke M A, McNicholl B, Fottrell P F, McCarthy C F

出版信息

J Clin Pathol. 1977 Jan;30(1):76-80. doi: 10.1136/jcp.30.1.76.

DOI:10.1136/jcp.30.1.76
PMID:320232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476650/
Abstract

The absorption of xylose following an oral load of 15 g D-xylose has been studied by serial blood levels in 17 untreated adult coeliac patients, 21 treated coeliac patients, and 30 non-coeliac patients. A statistically significant difference in xylose blood levels was found between untreated coeliac and non-coeliac patients at all the times studied, but a complete separation between these two groups occurred only at the 75 minute stage. The reproducibility of absorption was assessed by repeating the test in 16 subjects. The 95% confidence limits of the standard error of estimate are narrowest at 75 and 90 minutes.

摘要

通过检测17名未经治疗的成年乳糜泻患者、21名接受治疗的乳糜泻患者和30名非乳糜泻患者口服15克D-木糖后的系列血药浓度，研究了木糖的吸收情况。在所有研究时间点，未经治疗的乳糜泻患者和非乳糜泻患者的木糖血药浓度均存在统计学显著差异，但两组之间的完全分离仅出现在75分钟阶段。通过对16名受试者重复该试验评估吸收的可重复性。估计标准误差的95%置信区间在75分钟和90分钟时最窄。

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本文引用的文献

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The osmotic effects of some simple molecules and ions on gastric emptying.一些简单分子和离子对胃排空的渗透作用。
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The comparative rates of absorption of sugars from the human intestine.糖类在人体肠道中的吸收比较速率。
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D-Xylose blood-level time-curve as an index of intestinal absorption, with a description of a simplified method for estimation of blood xylose levels.以D-木糖血药浓度时间曲线作为肠道吸收指标，并描述一种估算血中木糖水平的简化方法。
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Coeliac disease. II. The presence in wheat of a factor having a deleterious effect in cases of coeliac disease.乳糜泻。II. 小麦中存在对乳糜泻患者有有害作用的一种因子。
Acta Paediatr (Stockh). 1953 Jan;42(1):34-42. doi: 10.1111/j.1651-2227.1953.tb05563.x.
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The slowing of gastric emptying by monosaccharides and disaccharides in test meals.测试餐中，单糖和双糖对胃排空的延缓作用。
J Physiol. 1968 Feb;194(2):317-26. doi: 10.1113/jphysiol.1968.sp008410.

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