Child and Adolescent Psychiatric Department, Region Zealand, Denmark; Psychiatric Research Unit, Region Zealand, Denmark; Child and Adolescent Psychiatric Department, Psychiatric Research Unit, University of Southern Denmark, Odense, Denmark.
Psychol Rep. 2021 Apr;124(2):479-501. doi: 10.1177/0033294120901846. Epub 2020 Feb 5.
Epigenetic research has pointed to that the interaction between genetics and environmental factors may play a role in making some individuals more vulnerable than others.
The aim of this article was to present a broad perspective on the current state of knowledge in a relatively new and complex field of "attachment and epigenetic processes."
We conducted a scoping review based on a systematic literature search in PsycINFO, PubMed, and Embase databases for relevant abstracts using the terms and .
In total, 11 studies were included. Research predating 2009 and animal studies were excluded in order to review the current state of research in humans.
Overall, there seems to be a consistency in the literature, pointing to a link between early childhood adversity, attachment processes, and epigenetic changes. However, research in human subjects is still limited.
表观遗传学研究指出，遗传与环境因素的相互作用可能使某些个体比其他个体更容易受到影响。
本文旨在对“依恋和表观遗传过程”这一相对较新且复杂的领域的现有知识状况进行广泛的概述。
我们在 PsycINFO、PubMed 和 Embase 数据库中进行了范围综述，使用术语 和 进行了系统的文献检索，以获取相关摘要。
共纳入了 11 项研究。为了综述当前人类研究的现状，排除了 2009 年之前的研究和动物研究。
总体而言，文献似乎存在一致性，表明儿童早期逆境、依恋过程和表观遗传变化之间存在联系。然而，人类研究仍然有限。
