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成人先天性心脏病患者胺碘酮所致甲状腺毒症的外科治疗:麻醉医师视角

Surgical Treatment of Amiodarone-Induced Thyrotoxicosis in an Adult with Congenital Heart Disease: An Anesthetists Perspective.

作者信息

El-Asmar Jose M, Naja Ahmad Salaheddine, Al-Halabi Eliane

机构信息

Division of Urology, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

Division of Orthopedics, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

Am J Case Rep. 2020 Feb 6;21:e917350. doi: 10.12659/AJCR.917350.

Abstract

BACKGROUND Amiodarone-induced thyrotoxicosis can be refractory to medical treatment seldom requiring surgical intervention. Herewith, we present the first case to date of amiodarone-induced thyrotoxicosis in a congenital heart disease post-Senning procedure requiring emergent surgical management. CASE REPORT A 19-year-old-male patient with a history of a complex congenital heart disease developed severe pulmonary baffle stenosis and atrial fibrillation that was medically treated with amiodarone, upon which he developed. Amiodarone-induced thyrotoxicosis that was refractory to medical treatment. The patient was taken to the operating room for surgical treatment of his refractory disease. An intraoperative transesophageal echocardiography was employed ensuring adequate monitoring of his systemic vascular resistance and pulmonary arterial pressures. CONCLUSIONS Because of the high risk of cardiac complications induced by thyroid-induced thyrotoxicosis, patients with complex congenital heart disease require careful intraoperative monitoring in anticipation of tragic events. This is a report of a single case of successful operation on a patient in the thyrotoxic state.

摘要

背景

胺碘酮所致甲状腺毒症可能对药物治疗无效,很少需要手术干预。在此,我们报告首例先天性心脏病Senning手术后发生胺碘酮所致甲状腺毒症且需要紧急手术治疗的病例。病例报告:一名19岁男性患者,有复杂先天性心脏病史,出现严重肺静脉分流狭窄和心房颤动,接受胺碘酮药物治疗后,发生了胺碘酮所致甲状腺毒症,且对药物治疗无效。该患者被送往手术室接受针对其难治性疾病的手术治疗。术中采用经食管超声心动图,确保对其体循环血管阻力和肺动脉压力进行充分监测。结论:由于甲状腺毒症所致心脏并发症风险高,复杂先天性心脏病患者在手术中需要仔细监测,以防发生严重事件。本文报告了1例处于甲状腺毒症状态患者成功手术的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d73/7020752/87bad2e8ac12/amjcaserep-21-e917350-g001.jpg

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