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一例罕见的普卢默-文森综合征病例。

A Rare Case of Plummer-Vinson Syndrome.

作者信息

Gade Ajay K, Pacheco Lauren

机构信息

Internal Medicine, Brookwood Baptist Medical Center, Birmingham, USA.

出版信息

Cureus. 2019 Dec 25;11(12):e6463. doi: 10.7759/cureus.6463.

DOI:10.7759/cureus.6463
PMID:32025392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6977583/
Abstract

Plummer-Vinson syndrome (PVS) is characterized by a triad of symptoms comprising microcytic hypochromic anemia, esophageal webs, and dysphagia. PVS is commonly found in women of middle age especially in the fourth and fifth decade of life and is rarely reported in males. We report a case of a 39-year-old female patient who had a classic presentation of PVS. PVS is precancerous with high malignant potential; early diagnosis is of utmost importance for better prognosis and surveillance endoscopy is recommended. Iron repletion oftentimes improves the dysphagia; seldom esophageal dilatation is used to provide symptomatic relief.

摘要

普卢默-文森综合征(PVS)的特征是由小细胞低色素性贫血、食管蹼和吞咽困难组成的三联征。PVS常见于中年女性,尤其是40至50岁的女性,男性中很少有报道。我们报告一例39岁女性患者,其具有PVS的典型表现。PVS是具有高恶性潜能的癌前病变;早期诊断对于更好的预后至关重要,建议进行监测性内镜检查。补充铁剂通常可改善吞咽困难;很少使用食管扩张术来缓解症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/760b/6977583/6944c74f73a7/cureus-0011-00000006463-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/760b/6977583/6944c74f73a7/cureus-0011-00000006463-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/760b/6977583/6944c74f73a7/cureus-0011-00000006463-i01.jpg

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本文引用的文献

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Am J Case Rep. 2019 Aug 27;20:1264-1267. doi: 10.12659/AJCR.916823.
2
Plummer-Vinson Syndrome with Esophageal Web Formation in which Detailed Endoscopic Images Were Obtained.伴有食管蹼形成的普卢默-文森综合征,并获取了详细的内镜图像。
Intern Med. 2019 Mar 15;58(6):785-789. doi: 10.2169/internalmedicine.1628-18. Epub 2018 Nov 19.
3
Iron deficiency anemia and Plummer-Vinson syndrome: current insights.
缺铁性贫血与普卢默-文森综合征:当前见解
J Blood Med. 2017 Oct 19;8:175-184. doi: 10.2147/JBM.S127801. eCollection 2017.
4
Plummer Vinson Syndrome: A Rare Syndrome in Male with Review of the Literature.普卢默-文森综合征:男性中的一种罕见综合征及文献综述
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Blood Cells Mol Dis. 2017 Jun;65:38-40. doi: 10.1016/j.bcmd.2017.04.002. Epub 2017 Apr 9.
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