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揭示普卢默-文森综合征:一例罕见病例报告

Unmasking Plummer-Vinson Syndrome: A Rare Case Report.

作者信息

Radhika B, Sekar Aswini, Gandhi Priyanka

机构信息

Associate Professor, Department of Periodontics, Chettinad Dental College and Research Institute, Kancheepuram, India.

Project Research Scientist, National Centre for Disease Informatics and Research (NCDIR), ICMR, Bengaluru, India.

出版信息

Contemp Clin Dent. 2025 Apr-Jun;16(2):132-135. doi: 10.4103/ccd.ccd_448_24. Epub 2025 Jul 14.

Abstract

This article highlights a unique case of Plummer-Vinson syndrome (PVS), also known as Paterson Brown-Kelly Syndrome. PVS is associated with a triad of symptoms, including microcytic hypochromic anemia, esophageal strictures, and dysphagia. It is commonly found in middle-aged women, particularly in the fourth and fifth decades of life, and is rarely reported in males. We present the case of a 49-year-old female patient who exhibited the classic symptoms of PVS. Given that PVS is a precancerous condition with a high potential for malignancy, early diagnosis is crucial for a better prognosis. Surveillance endoscopy and barium swallow test are recommended for monitoring. Iron repletion often improves dysphagia, and in some cases, esophageal dilatation is used to provide symptomatic relief. The mutual interaction of systemic and oral health is often underestimated, especially by patients in developing countries. Therefore, this report emphasizes the importance of thorough medical history taking and its relevance to dental health and treatment.

摘要

本文重点介绍了一例独特的普卢默-文森综合征(PVS)病例,该综合征也被称为帕特森-布朗-凯利综合征。PVS与一组三联征症状相关,包括小细胞低色素性贫血、食管狭窄和吞咽困难。它常见于中年女性,尤其是在40至50岁之间,在男性中很少见。我们报告了一名49岁女性患者,她表现出PVS的典型症状。鉴于PVS是一种具有高恶性潜能的癌前疾病,早期诊断对于改善预后至关重要。建议进行监测性内镜检查和吞钡试验。补充铁剂通常可改善吞咽困难,在某些情况下,可采用食管扩张术来缓解症状。全身健康与口腔健康之间的相互作用常常被低估,尤其是发展中国家的患者。因此,本报告强调了全面采集病史的重要性及其与口腔健康和治疗的相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9021/12338457/d2c8d333939d/CCD-16-132-g001.jpg

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