改善老年和糖尿病肥胖小鼠的术后结局
Improving Post-Operative Outcomes in Aged and Diabetic Obese Mice.
作者信息
Szilagyi Keely, Zieger Michael A, Li Jiliang, Kacena Melissa A
机构信息
Laboratory Animal Resource Center at the Indiana University School of Medicine, Indianapolis, IN.
Indiana University School of Medicine, Indianapolis, IN.
出版信息
Lab Animal Sci Prof. 2018 Sep;6(3):65-67.
Abstract
Due to their small size, high metabolic rate, and large surface to volume ratio, mice are a challenge to work with surgically and pre-operatively. Working with mice that are more susceptible to anesthetic agents, aged, or obese (e.g., diabetic mice), provides even more challenges. In two separate studies, we found simple that supportive care measures during and after surgery improved post-operative outcomes.
摘要
由于小鼠体型小、代谢率高且表面积与体积比大，在手术和术前对其进行操作具有挑战性。处理对麻醉剂更敏感、年老或肥胖的小鼠（如糖尿病小鼠），会带来更多挑战。在两项独立研究中，我们发现，手术期间及术后的简单支持性护理措施可改善术后结果。
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