Yang Jiamiao, Li Jingwei, He Sailing, Wang Lihong V
Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, California 91125, USA.
Centre for Optical and Electromagnetic Research, Chinese National Engineering Research Center for Optical Instruments, Zhejiang University, Hangzhou 310058, China.
Optica. 2019 Mar 20;6(3):250-256. doi: 10.1364/optica.6.000250.
Focusing light inside scattering media by optical phase conjugation has been intensively investigated due to its potential applications, such as in deep tissue imaging. However, no existing physical models explain the impact of the various factors on the focusing performance inside a dynamic scattering medium. Here, we establish an angular- spectrum model to trace the field propagation during the entire optical phase conjugation process in the presence of scattering media. By incorporating fast decorrelation components, the model enables us to investigate the com- petition between the guide star and fast tissue motions for photon tagging. Other factors affecting the focusing performance are also analyzed via the model. As a proof of concept, we experimentally verify our model in the case of focusing light through dynamic scattering media. This angular-spectrum model allows analysis of a series of scattering events in highly scattering media and benefits related applications.
由于其在诸如深层组织成像等潜在应用，通过光学相位共轭在散射介质内部聚焦光已得到深入研究。然而，现有的物理模型均无法解释各种因素对动态散射介质内部聚焦性能的影响。在此，我们建立了一个角谱模型，以追踪在存在散射介质的整个光学相位共轭过程中的场传播。通过纳入快速去相关分量，该模型使我们能够研究导星与快速组织运动在光子标记方面的竞争。影响聚焦性能的其他因素也通过该模型进行了分析。作为概念验证，我们在通过动态散射介质聚焦光的情况下对我们的模型进行了实验验证。这个角谱模型允许对高散射介质中的一系列散射事件进行分析，并有利于相关应用。
