Unit of Urogynecology, Department of Obstetrics and Gynecology, University of Insubria, Varese, Italy -
Unit of Urology, Department of Surgical Sciences, Tor Vergata University Hospital, Rome, Italy.
Minerva Urol Nefrol. 2020 Aug;72(4):420-426. doi: 10.23736/S0393-2249.20.03685-1. Epub 2020 Jan 30.
Overactive bladder (OAB) is a common clinical condition affecting women. The impact of urodynamics (UDS) on the management of idiopathic OAB in women is highly debated. This systematic review analyzes the impact of UDS on the choice and on the outcomes of treatment of female idiopathic OAB.
A systematic literature search in the PubMed/Medline, Web of Science, Scopus and Cochrane databases was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis statement to identify clinical trials, randomized controlled trials, meta-analyses, and guidelines on female OAB and UDS published from 2000. A total of 1554 records were initially identified and 12 articles were included in the final qualitative synthesis.
UDS represents the main tool to diagnose detrusor overactivity (DO) in OAB female patients which is considered one of the major OAB underlying pathophysiology factor. UDS can underline the presence of voiding dysfunction that could be considered as another underlying cause of uncomplicated female OAB. On the basis of this urodynamic findings, we can better define different aspects of OAB syndrome leading to a more tailored and proper treatment.
UDS can have a useful role in the diagnosis of idiopathic OAB in women given the possibility to gain a precise diagnosis and, therefore, a tailored treatment based on the underlying cause. The integration of clinics with UDS and all the other diagnostic available tools is desirable.
膀胱过度活动症（OAB）是一种常见的影响女性的临床病症。尿动力学检查（UDS）对女性特发性 OAB 的管理的影响存在很大争议。本系统评价分析了 UDS 对女性特发性 OAB 治疗选择和治疗结果的影响。
根据系统评价和荟萃分析的首选报告项目声明，在 PubMed/Medline、Web of Science、Scopus 和 Cochrane 数据库中进行了系统的文献检索，以确定自 2000 年以来发表的关于女性 OAB 和 UDS 的临床试验、随机对照试验、荟萃分析和指南。最初确定了 1554 条记录，最终纳入了 12 篇文章进行定性综合分析。
UDS 是诊断 OAB 女性患者逼尿肌过度活动（DO）的主要工具，被认为是 OAB 主要潜在病理生理学因素之一。UDS 可以发现排尿功能障碍，这可能被认为是女性单纯性 OAB 的另一个潜在原因。基于这些尿动力学发现，我们可以更好地定义 OAB 综合征的不同方面，从而进行更有针对性和适当的治疗。
鉴于 UDS 有可能获得准确的诊断，从而根据潜在原因进行针对性治疗，因此在女性特发性 OAB 的诊断中可以发挥有用的作用。将诊所与 UDS 以及所有其他可用的诊断工具相结合是理想的。
