Schwartze G
Klinik und Poliklinik für Hautkrankheiten der Bereiches Medizin, Martin-Luther-Universität Halle, Wittenberg.
Arch Geschwulstforsch. 1988;58(5):341-4.
Comparing the monthly indole melanogen mean values (4,100 single values within 5 years) in patients with malignant melanomas showing a normal urinary indole melanogen concentration we have found a seasonal effect with a maximum melanogen excretion in spring (March) and summer (July) and a minimum in autumn (September). These results are statistically significant. The possible importance of these seasonal influences for the prognosis in individual cases of malignant melanoma is discussed.
