Fornazari Vinicius Adami Vayego, Salazar Gloria Maria Martinez, Vayego Stela Adami, Nunes Thiago Franchi, Goncalves Belarmino, Szejnfeld Jacob, Bonduki Claudio Emilio, Goldman Suzan Menasce, Szejnfeld Denis
Interventional Radiology and Endovascular Surgery, Universidade Federal de São Paulo (UNIFESP), Rua Napoleão de Barros, 800, Vila Clementino, São Paulo, SP, 04024-002, Brazil.
Department of Simulation and Patient Experience, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St #290, Boston, MA, 02114, USA.
CVIR Endovasc. 2019 Nov 12;2(1):36. doi: 10.1186/s42155-019-0080-2.
Although changes in uterine contractility pattern after uterine fibroid embolization (UFE) has already been assessed by cine magnetic resonance imaging (MRI), their impact on quality of life outcomes has not been evaluated. The purpose of this study was to evaluate the impact of uterine contractility on the quality of life of women undergoing UFE measured by the Uterine Fibroid Symptom and Quality of Life questionnaire (UFS-QOL).
A total of 26 patients were included. MRI scans were acquired 30-7 days before and 6 months after UFE for all patients. The UFS-QOL was applied in person on first MRI exam day and 1 year after UFE and the outcomes were analyzed according to the groups of evolution pattern of uterine contractility: Group A: Unchanged Uterine Contractility Pattern, 38%; Group B: Favorable Modified Uterine Contractility Pattern, 50%; and Group C: Loss of Uterine Contractility, 11%. All UFE patients presented a reduction in the mean score for symptoms and increase in mean scores on quality of life. All patients in this cohort presented a reduction in mean symptom score and increase in the mean score of quality of life subscales. Group A had more relevant complaints regarding their sense of self-confidence; Group B presented worse sexual function scores before UFE, which improved after UFE compared to Group A.
Significant improvement in symptoms, quality of life, and uterine contractility was observed after UFE in women of reproductive age with symptomatic fibroids. Functional uterine contractility seems to have a positive impact on quality of life and sexual function in this population.
Level 3, Non-randomized controlled cohort/follow-up study.
尽管子宫平滑肌瘤栓塞术（UFE）后子宫收缩模式的变化已通过电影磁共振成像（MRI）进行了评估，但其对生活质量结果的影响尚未得到评估。本研究的目的是通过子宫肌瘤症状与生活质量问卷（UFS-QOL）评估子宫收缩对接受UFE治疗的女性生活质量的影响。
共纳入26例患者。所有患者在UFE前30 - 7天和术后6个月进行了MRI扫描。在首次MRI检查日和UFE后1年亲自应用UFS-QOL，并根据子宫收缩演变模式组分析结果：A组：子宫收缩模式不变，占38%；B组：有利的改良子宫收缩模式，占50%；C组：子宫收缩丧失，占11%。所有UFE患者的症状平均评分降低，生活质量平均评分升高。该队列中的所有患者症状平均评分降低，生活质量子量表平均评分升高。A组在自信心方面有更多相关抱怨；B组在UFE前性功能评分较差，与A组相比，UFE后有所改善。
在有症状的子宫肌瘤育龄妇女中，UFE后症状、生活质量和子宫收缩均有显著改善。功能性子宫收缩似乎对该人群的生活质量和性功能有积极影响。
3级，非随机对照队列/随访研究。
