Department of Medical Engineering, Aino University, Ibaraki, Osaka, Japan.
Noda Clinic, Miyakonojo-shi, Miyazaki, Japan.
PLoS One. 2020 Feb 6;15(2):e0228630. doi: 10.1371/journal.pone.0228630. eCollection 2020.
The relevance between time-series fetal heart rate (FHR) pattern changes during labor and outcomes such as arterial blood gas data at delivery has not been studied. Using 3-tier and 5-tier classification systems, we studied the relationship between time-series FHR pattern changes before delivery and umbilical artery blood gas data at delivery.
The subjects were 1,909 low-risk women with vaginal delivery (age: 29.1 ± 4.4 years, parity: 1.7 ± 0.8). FHR patterns were classified by a skilled obstetrician based on each 10 min-segment of the last 60 min before delivery from continuous CTG records in an obstetric clinic.
The relationship between each 10 min-segment FHR pattern classification from 60 minutes before delivery and umbilical artery blood pH and base excess (BE) values at delivery changed with time. In the 3-tier classification, mean pH of Category I group in each 10 min-segment was significantly higher than that of Category II group. For Category I groups in each 10-minute segment, its number decreased and its average pH increased as the delivery time approached. In the 5-tier classification, there was the same tendency. About each level group in 10 min-segment, the higher the level, the lower the blood gas values, and mean pH of higher level groups decreased as the delivery time approached.
The relationship between classifications and outcomes was clear at any time from 60 min before delivery in 3- and 5-tier classifications, and the 5-tier classification was more relevant.
分娩期间胎儿心率(FHR)时间序列模式变化与分娩时动脉血气数据等结果之间的相关性尚未得到研究。使用 3 级和 5 级分类系统,我们研究了分娩前 FHR 时间序列模式变化与分娩时脐动脉血气数据之间的关系。
本研究的对象是 1909 名低危阴道分娩的女性(年龄:29.1±4.4 岁,产次:1.7±0.8)。FHR 模式由熟练的产科医生根据分娩前最后 60 分钟连续 CTG 记录中的每 10 分钟片段进行分类。
分娩前 60 分钟每个 10 分钟片段的 FHR 模式分类与分娩时脐动脉 pH 值和碱剩余(BE)值之间的关系随时间而变化。在 3 级分类中,每个 10 分钟片段中 I 类组的平均 pH 值显著高于 II 类组。对于每个 10 分钟片段的 I 类组,随着分娩时间的临近,其数量减少,平均 pH 值升高。在 5 级分类中,也存在相同的趋势。在每个 10 分钟片段的每个级别组中,级别越高,血气值越低,并且随着分娩时间的临近,较高级别组的平均 pH 值降低。
在 3 级和 5 级分类中,从分娩前 60 分钟开始的任何时间,分类与结果之间的关系都很明确,并且 5 级分类更相关。