National Health Insurance Service Ilsan Hospital, Goyang, South Korea.
Cardiology Division, Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, South Korea.
Heart Rhythm. 2020 Jun;17(6):931-936. doi: 10.1016/j.hrthm.2020.01.026. Epub 2020 Feb 4.
Few data on the association between height and the risk of sudden cardiac death (SCD) in Asian populations are available.
The purpose of this study was to assess the risk of SCD as related to height both in a representative Korean population and in specific subgroups.
This is a retrospective cohort study of 410,119 Koreans age ≥20 years from the Korean National Health Insurance Service-National Sample Cohort, who underwent a national health examination. SCD cases were adjudicated based on information within the claims database. Cox proportional hazard models were applied to estimate hazard ratios and 95% confidence intervals for the association between height and SCD. Potential mediators included demographic factors, health-related habits, and specific cardiovascular comorbidities.
During an 8.45-year follow-up period, a total of 1341 SCDs occurred. Various factors, including short stature, were identified as risk factors for SCD. Multivariable regression analysis revealed that a 10-cm increase in height was associated with a 14% decreased risk for SCD. This relationship remained significant among the elderly, postmenopausal women, and individuals without cardiovascular disease.
Our results indicate that short stature is a significant risk factor for SCD in a Korean population, thus supporting previously published findings correlating height to SCD risk in non-Asian populations.
亚洲人群中关于身高与心源性猝死（SCD）风险之间关联的资料很少。
本研究旨在评估身高与 SCD 风险之间的关联，在代表性的韩国人群以及特定亚组人群中均进行评估。
这是一项回顾性队列研究，纳入了 410119 名年龄≥20 岁的韩国国民健康保险服务-国家抽样队列人群，他们接受了国家健康体检。SCD 病例根据理赔数据库中的信息进行裁决。应用 Cox 比例风险模型来估计身高与 SCD 之间的关联的风险比和 95%置信区间。潜在的中介因素包括人口统计学因素、健康相关习惯和特定心血管合并症。
在 8.45 年的随访期间，共发生了 1341 例 SCD。各种因素，包括身材矮小，被确定为 SCD 的危险因素。多变量回归分析显示，身高增加 10cm，SCD 的风险降低 14%。这种关系在老年人、绝经后妇女和无心血管疾病的人群中仍然显著。
我们的研究结果表明，身材矮小是韩国人群中 SCD 的一个显著危险因素，因此支持了先前发表的关于身高与非亚洲人群 SCD 风险相关的研究结果。
