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一期后路全脊椎整块切除术治疗腰椎转移瘤。

Single-stage posterior total en bloc spondylectomy in the treatment of lumbar spinal metastases.

机构信息

Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing, People's Republic of China.

出版信息

Clin Neurol Neurosurg. 2020 Apr;191:105645. doi: 10.1016/j.clineuro.2019.105645. Epub 2019 Dec 20.

Abstract

OBJECTIVE

To report the clinical and radiographic outcomes of single-stage posterior total en bloc spondylectomy (TES) of lumbar spinal metastases.

PATIENTS AND METHODS

From January 2012 to January 2015, 20 consecutive cases with lumbar spinal metastases who received single-stage posterior TES were retrospectively analyzed. A visual analog scale (VAS) was used to evaluate patients' pain status, American Spinal Injury Association (ASIA) classification was used to evaluate neurological status, and Eastern Cooperative Oncology Group (ECOG) score system was used to evaluate patients' performance status at pre- and post-operation and final follow-up. In addition, Intraoperative blood loss, operative time, postoperative complications, local kyphosis angle, and the postoperative duration of hospital stay were analyzed.

RESULTS

The median follow-up time was 16 months (ranging from 3 to 39 months), and 4 patients were still alive at the last follow-up. The mean amount of intraoperative blood loss and operation time was 970 mL and 232.5 min, respectively. The average VAS score improved from 7.5 preoperative to 2.8 postoperative and 3.2 at the last follow-up. Postoperative complications occurred in 3 cases. Sixteen patients died within 2 years after surgery, 10 of which died within 1 year. In the remaining 4 patients, the mean follow-up period was 37.25 months. One case of local recurrence occurred but no implant failure presented during follow-up.

CONCLUSIONS

Single-stage posterior TES is a challenging but rewarding procedure in the treatment of lumbar spinal metastases. Due to unique anatomy and biomechanics, surgeons should be aware of important vessels, and nerve root injury should be avoided.

摘要

目的

报告单阶段后路全脊椎整块切除术(TES)治疗腰椎脊柱转移瘤的临床和影像学结果。

方法

回顾性分析 2012 年 1 月至 2015 年 1 月期间接受单阶段后路 TES 的 20 例腰椎脊柱转移瘤患者。采用视觉模拟评分(VAS)评估患者疼痛状况,采用美国脊柱损伤协会(ASIA)分级评估神经状况,采用东部肿瘤协作组(ECOG)评分系统评估患者术前、术后和最终随访时的功能状态。此外,分析术中出血量、手术时间、术后并发症、局部后凸角和术后住院时间。

结果

中位随访时间为 16 个月(3 至 39 个月),末次随访时仍有 4 例患者存活。术中出血量和手术时间的平均值分别为 970ml 和 232.5min。术前 VAS 评分为 7.5,术后为 2.8,末次随访时为 3.2。术后发生 3 例并发症。术后 2 年内 16 例患者死亡,其中 10 例在术后 1 年内死亡。在其余 4 例患者中,平均随访时间为 37.25 个月。随访期间发生 1 例局部复发,但无植入物失败。

结论

单阶段后路 TES 是治疗腰椎脊柱转移瘤的一项具有挑战性但有价值的手术。由于独特的解剖结构和生物力学,外科医生应注意重要的血管,避免神经根损伤。

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