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一种使用 6 和 15 MV 光子束时通过 TLD 在骨和肺中定量剂量的实用方法。

A practical method for quantifying dose in bone and lung using TLDs when using 6 and 15 MV photon beams.

机构信息

Institute of Nuclear Science, Hacettepe University, 06532 Ankara, Turkey. Both authors contributed equally to this manuscript.

出版信息

Phys Med Biol. 2020 Mar 6;65(5):05NT01. doi: 10.1088/1361-6560/ab735d.

Abstract

This paper presents a practical method for converting dose measured with thermoluminescent dosimeters (TLD) to dose in lung and bone for 6 MV and 15 MV photon beams. Monte Carlo (MC) simulations and Burlin cavity theory calculations were performed to calculate [Formula: see text], the dose-to-TLD to dose-to-medium conversion factor. A practical method was proposed for converting TLD-measured-dose to dose-in-medium using the TLD dose calibration in water and [Formula: see text] dose-to-medium to dose-to-water conversion factor. Theoretical calculations for [Formula: see text] were performed using photon spectrum weighted parameters and were compared with MC simulations. Verification of the proposed method was done using phantoms having either bone or lung equivalent slabs stacked in between solid water slabs. Percent depth dose (PDD) curves were measured using 0.089 cm thick LiF:Mg,Ti (TLD-100) dosemeters placed at various depths within these phantoms. They were then corrected with [Formula: see text] factors using the proposed dose conversion method, and were compared with the MC simulations. For 6 MV beam, the MC calculated [Formula: see text] factors were 0.942 and 1.002 for bone and lung, and for 15 MV it was 0.927 and 1.005 for bone and lung, respectively. The difference between the MC simulated and spectrum weighted theoretical [Formula: see text] factors were within 3% for both lung and bone. The PDD curves measured with TLD-100 chips that were corrected using the proposed method agreed well within 1.5% of the MC simulated PDD curves for both the water/lung/water and water/bone/water (WBW) phantoms. The dose-to-medium correction using MC simulated [Formula: see text] is convenient, easy, and accurate. Therefore, it can be used instead of Burlin cavity theory, especially in media with high atomic numbers such as bone for accurate dose quantification.

摘要

本文提出了一种实用的方法,用于将用热释光剂量计(TLD)测量的剂量转换为 6 MV 和 15 MV 光子束的肺和骨中的剂量。通过蒙特卡罗(MC)模拟和 Burlin 空腔理论计算,计算了[Formula: see text],即 TLD 剂量与介质剂量的转换因子。提出了一种实用的方法,用于使用 TLD 在水中的剂量校准和[Formula: see text]将 TLD 测量的剂量转换为介质中的剂量。使用光子谱加权参数对[Formula: see text]进行了理论计算,并与 MC 模拟进行了比较。使用在固体水块之间堆叠有骨等效或肺等效平板的体模验证了所提出的方法。使用 0.089 cm 厚的 LiF:Mg,Ti(TLD-100)剂量计在这些体模内的各个深度处测量了百分深度剂量(PDD)曲线。然后,使用所提出的剂量转换方法,用[Formula: see text]因子进行校正,并与 MC 模拟进行比较。对于 6 MV 束,MC 计算的[Formula: see text]因子分别为骨和肺中的 0.942 和 1.002,而对于 15 MV,骨和肺中的[Formula: see text]因子分别为 0.927 和 1.005。MC 模拟和谱加权理论[Formula: see text]因子之间的差异在肺和骨中均小于 3%。使用 TLD-100 芯片测量的 PDD 曲线,使用所提出的方法进行校正后,与 MC 模拟的 PDD 曲线在水/肺/水和水/骨/水(WBW)体模中的吻合度均在 1.5%以内。使用 MC 模拟的[Formula: see text]进行介质剂量校正既方便又准确。因此,它可以代替 Burlin 空腔理论,特别是在骨等高原子数的介质中,用于准确的剂量量化。

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