从. 中分离得到两种新的齐墩果烷型三萜皂苷。
Two new oleanane triterpenoid saponins from .
机构信息
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
出版信息
Nat Prod Res. 2021 Nov;35(21):3658-3666. doi: 10.1080/14786419.2020.1721489. Epub 2020 Feb 6.
Two new oleanane triterpenoid saponins, bodiniosides Q () and R (), along with five known saponins, niga-ichigoside F1 (), 3--[-D-glucopyranosyl]-28--[-L-rhamnopyranosyl -(1→2)--D-glucopyranosyl] arjunolic acid (), asiaticoside E (), sericoside (), and bodinioside E (), were isolated from the aerial parts of . The structures of and were characterized by spectroscopic techniques and chemical evidence as 3---D- xylopyranosyl-2, 23-dihydroxy-olean-12-en-28-oic acid 28---L-rhamnopyranosyl- (1→2)--D-glucopyranoside () and 3---D-xylopyranosyl-2, 23-dihydroxy-olean-12-en-28-oic acid 28--[-D-glucopyranosyl-(1→4)--L-rhamnopyranosyl -(1→2)]--D-glucopyranoside (). Compounds , , and exhibited weak anti-influenza activity against strain A/WSN/33/2009 (H1N1), with inhibition rate of 11.63%, 17.01%, and 16.98%, respectively.
从 bodin 的地上部分分离得到两种新的齐墩果烷三萜皂苷，bodiniosides Q()和 R()，以及五种已知的皂苷，niga-ichigoside F1()、3--[-D-吡喃葡萄糖基]-28--[-L-鼠李吡喃糖基-(1→2)--D-吡喃葡萄糖基]齐墩果酸()、asiaticoside E()、丝氨酸苷()和 bodinioside E()。和通过光谱技术和化学证据鉴定为 3---D-木糖基-2,23-二羟基齐墩果酸 28---L-鼠李吡喃糖基-(1→2)--D-吡喃葡萄糖苷()和 3---D-木糖基-2,23-二羟基齐墩果酸 28--[-D-吡喃葡萄糖基-(1→4)--L-鼠李吡喃糖基-(1→2)]--D-吡喃葡萄糖苷()。化合物、和对 A/WSN/33/2009(H1N1)株表现出较弱的抗流感活性，抑制率分别为 11.63%、17.01%和 16.98%。
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