博迪尼苷 S-Y，从 中分离得到的七种新三萜皂苷及其抗流感活性。
Bodiniosides S-Y, Seven New Triterpenoid Saponins from and Their Anti-Influenza Activities.
机构信息
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Medical School, Kunming University of Science and Technology, Kunming 650500, China.
出版信息
Molecules. 2021 Oct 29;26(21):6535. doi: 10.3390/molecules26216535.
Investigation of the n-BuOH extract of the aerial parts of led to the isolation of seven new triterpenoid saponins, Bodiniosides S-Y (-, resp.). Their strictures were elucidated on the basis of spectroscopic techniques, including HSQC, HSBC, and HSQC-TOCSY experiments, together with acid hydrolysis and GC analysis. The anti-influenza activities of compounds - were evaluated against A/WSN/33/2009 (H1N1) virus in MDCK cells. The results showed that compounds and exhibited moderate anti-influenza activities against A/WSN/33/2009 (H1N1), with inhibition rates of 35.33% and 24.08%, respectively.
从 led 的地上部分的正丁醇提取物中分离得到了七种新的三萜皂苷，分别命名为 Bodiniosides S-Y（-）。基于包括 HSQC、HSBC 和 HSQC-TOCSY 实验在内的光谱技术以及酸水解和 GC 分析，阐明了它们的结构。在 MDCK 细胞中，对化合物 - 进行了针对 A/WSN/33/2009（H1N1）病毒的抗流感活性评估。结果表明，化合物 和 对 A/WSN/33/2009（H1N1）具有中等的抗流感活性，抑制率分别为 35.33%和 24.08%。
Zotero 插件