Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.
Medical School, Kunming University of Science and Technology, Kunming 650500, China.
Molecules. 2021 Oct 29;26(21):6535. doi: 10.3390/molecules26216535.
Investigation of the n-BuOH extract of the aerial parts of led to the isolation of seven new triterpenoid saponins, Bodiniosides S-Y (-, resp.). Their strictures were elucidated on the basis of spectroscopic techniques, including HSQC, HSBC, and HSQC-TOCSY experiments, together with acid hydrolysis and GC analysis. The anti-influenza activities of compounds - were evaluated against A/WSN/33/2009 (H1N1) virus in MDCK cells. The results showed that compounds and exhibited moderate anti-influenza activities against A/WSN/33/2009 (H1N1), with inhibition rates of 35.33% and 24.08%, respectively.
从 led 的地上部分的正丁醇提取物中分离得到了七种新的三萜皂苷，分别命名为 Bodiniosides S-Y（-）。基于包括 HSQC、HSBC 和 HSQC-TOCSY 实验在内的光谱技术以及酸水解和 GC 分析，阐明了它们的结构。在 MDCK 细胞中，对化合物 - 进行了针对 A/WSN/33/2009（H1N1）病毒的抗流感活性评估。结果表明，化合物 和 对 A/WSN/33/2009（H1N1）具有中等的抗流感活性，抑制率分别为 35.33%和 24.08%。
