Department of Hematology and Cancer Prevention in Chorzów, Faculty of Public Health in Bytom, Medical University of Silesia in Katowice, Katowice, Poland.
Expert Rev Hematol. 2020 Mar;13(3):201-212. doi: 10.1080/17474086.2020.1727738. Epub 2020 Feb 13.
: According to estimates based on the GLOBOCAN database of the International Agency for Research on Cancer, in 2018 alone, 18 100 000 cancers were globally diagnosed. Importantly, the majority of cancer patients experience unintended weight loss that leads to many adverse clinical consequences, including malnutrition and cancer cachexia. At the same time, each nutritional intervention must be carried out individually, as it can lead to critical complications, resulting in a threat to the health and life of the cachectic patient. An example of this type of risk is refeeding syndrome.: Three factors seem to be crucial in this case: early identification of patients at risk of malnutrition, the introduction of an individualized diet regimen and constant monitoring of nutritional intervention. It seems equally important to spread awareness about the possibility of refeeding syndrome and knowledge about its patomechanisms and consequences among medical staff. This should lead to minimizing the risk of refeeding syndrome.: It should be noted that current guidelines on the pathogenesis, risk factors and methods of prevention and treatment of refeeding syndrome require further modifications, that would harmonize the management regimen in both prevention and therapy of refeeding syndrome.
根据国际癌症研究机构全球癌症数据库的估计，仅在 2018 年，全球就诊断出 1810 万例癌症。重要的是，大多数癌症患者经历了意外的体重减轻，导致许多不良的临床后果，包括营养不良和癌症恶病质。同时，必须对每个营养干预措施进行个体化实施，因为这可能导致严重的并发症，从而对恶病质患者的健康和生命构成威胁。这种类型的风险的一个例子是再喂养综合征。在这种情况下，似乎有三个因素至关重要：早期识别有营养不良风险的患者、引入个体化饮食方案以及对营养干预的持续监测。同样重要的是，要提高医务人员对再喂养综合征的可能性以及对其发病机制和后果的认识。这应有助于将再喂养综合征的风险降至最低。值得注意的是，目前关于再喂养综合征的发病机制、危险因素以及预防和治疗方法的指南需要进一步修改，以协调预防和治疗再喂养综合征的管理方案。
