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先天性雄激素缺乏患者语言和空间任务的偏侧化模式及表现水平

Patterns of lateralization and performance levels for verbal and spatial tasks in congenital androgen deficiency.

作者信息

Cappa S F, Guariglia C, Papagno C, Pizzamiglio L, Vallar G, Zoccolotti P, Ambrosi B, Santiemma V

机构信息

Divisione Neurologica, Ospedale Niguarda-Cà Granda, Milan, Italy.

出版信息

Behav Brain Res. 1988 Dec 1;31(2):177-83. doi: 10.1016/0166-4328(88)90021-6.

DOI:10.1016/0166-4328(88)90021-6
PMID:3202949
Abstract

The effects of congenital deficiency of gonadal hormones on verbal and spatial performance and on the establishment of hemispheric asymmetries were investigated in a group of patients with idiopathic hypogonadotropic hypogonadism. The patients showed a left hemispheric advantage for verbal material and were mildly impaired, mainly on tasks involving a short-term memory load, in comparison with a matched control group. These results do not indicate a specific role of gonadal hormones on the establishment of hemispheric asymmetries. Lack of exposure during brain development results in a decrease in memory functions which is not specific for verbal or spatial material.

摘要

在一组特发性低促性腺激素性性腺功能减退患者中,研究了先天性性腺激素缺乏对语言和空间能力以及半球不对称性建立的影响。与匹配的对照组相比,这些患者在语言材料方面表现出左半球优势,并且主要在涉及短期记忆负荷的任务上有轻度受损。这些结果并未表明性腺激素在半球不对称性建立中具有特定作用。大脑发育期间缺乏激素暴露会导致记忆功能下降,这并非语言或空间材料所特有。

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