神经丝轻链和C反应蛋白作为肌萎缩侧索硬化症生存预测指标的研究 - Suppr

Neurofilament light chain and C reactive protein explored as predictors of survival in amyotrophic lateral sclerosis.

作者信息

De Schaepdryver Maxim, Lunetta Christian, Tarlarini Claudia, Mosca Lorena, Chio Adriano, Van Damme Philip, Poesen Koen

机构信息

Department of Neurosciences, Leuven Brain Institute, Laboratory for Molecular Neurobiomarker Research, KU Leuven, Leuven, Belgium.

NEuroMuscular Omnicenter (NEMO), Fondazione Serena Onlus, Milan, Italy.

出版信息

J Neurol Neurosurg Psychiatry. 2020 Apr;91(4):436-437. doi: 10.1136/jnnp-2019-322309. Epub 2020 Feb 6.

DOI:10.1136/jnnp-2019-322309

PMID:32029541

Abstract

摘要

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Neurofilament light chain and C reactive protein explored as predictors of survival in amyotrophic lateral sclerosis.神经丝轻链和C反应蛋白作为肌萎缩侧索硬化症生存预测指标的研究

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Serial measurements of phosphorylated neurofilament-heavy in the serum of subjects with amyotrophic lateral sclerosis.对肌萎缩侧索硬化症患者血清中磷酸化神经丝重链进行系列测量。

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Serum neurofilament light chain at time of diagnosis is an independent prognostic factor of survival in amyotrophic lateral sclerosis.诊断时的血清神经丝轻链是肌萎缩侧索硬化症生存的独立预后因素。

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Neurofilament light chain and C reactive protein explored as predictors of survival in amyotrophic lateral sclerosis.

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