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原发性自发性气胸肺大疱切除术的最佳切缘距离可降低术后复发率。

Optimal margin distance of bullectomy for primary spontaneous pneumothorax reduces postoperative recurrence.

作者信息

Tsuboshima Kenji, Matoba Yasumi, Wakahara Teppei

机构信息

Department of Thoracic Surgery and Pneumothorax Center, Takasago Municipal Hospital, Takasago, Japan.

出版信息

J Thorac Dis. 2019 Dec;11(12):5115-5123. doi: 10.21037/jtd.2019.12.06.

Abstract

BACKGROUND

For primary spontaneous pneumothorax, bullectomy using autosutures is the standard procedure. Despite performing various methods for preventing postoperative recurrence, it remains relatively high. Although considering the margin distance of bullectomy is important, no argument has been discussed for the optical margin distance until now. Hence, we evaluated the optimal margin distance for bullectomy of spontaneous pneumothorax, bullectomy to reduce postoperative recurrence.

METHODS

Between March 2015 and May 2018, 91 eligible candidates from 142 cases, who underwent video-assisted thoracoscopic bullectomy for spontaneous pneumothorax, bullectomy, were evaluated. We analysed the factors preventing postoperative recurrence, including the margin distance using the inverse-probability of treatment weighted method by propensity score was used to adjust for heterogeneous patient backgrounds.

RESULTS

The patients' median age was 20 years (range, 14-86 years). Postoperative recurrences occurred in 8 cases (8.8%). The margin distance was 9.1±5.0 mm. The cut-off point of the margin distance was defined as 5.0 mm. The inverse-probability of treatment weighted method indicated that a margin distance ≥5.0 mm significantly prevented postoperative recurrence (P=0.0076, hazard ratio =0.18).

CONCLUSIONS

This study suggests that a margin distance of ≥5.0 mm for bullectomy of PSP can reduce postoperative recurrence.

摘要

背景

对于原发性自发性气胸,使用自动缝合器进行肺大疱切除术是标准手术。尽管采用了各种预防术后复发的方法,但复发率仍然相对较高。虽然考虑肺大疱切除术的切缘距离很重要,但迄今为止尚未讨论过理想的切缘距离。因此,我们评估了自发性气胸肺大疱切除术的最佳切缘距离,以减少术后复发。

方法

在2015年3月至2018年5月期间,对142例行电视辅助胸腔镜下自发性气胸肺大疱切除术的患者中的91例符合条件的患者进行了评估。我们分析了预防术后复发的因素,包括使用倾向评分的治疗加权逆概率方法来调整不同患者背景的切缘距离。

结果

患者的中位年龄为20岁(范围14 - 86岁)。术后复发8例(8.8%)。切缘距离为9.1±5.0毫米。切缘距离的截断点定义为5.0毫米。治疗加权逆概率方法表明,切缘距离≥5.0毫米可显著预防术后复发(P = 0.0076,风险比 = 0.18)。

结论

本研究表明原发性自发性气胸肺大疱切除术切缘距离≥5.0毫米可降低术后复发率。

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