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体能参数与老年人脑白质微观结构的关系:一项弥散张量成像研究。

The association between physical fitness parameters and white matter microstructure in older adults: A diffusion tensor imaging study.

机构信息

Graduate Institute of Sport, Leisure and Hospitality Management, National Taiwan Normal University, Taipei, Republic of China (Taiwan).

Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.

出版信息

Psychophysiology. 2020 May;57(5):e13539. doi: 10.1111/psyp.13539. Epub 2020 Feb 6.

DOI:10.1111/psyp.13539
PMID:32030777
Abstract

The present study was designed to examine whether different measures of physical fitness are differentially associated with white matter (WM) microstructure in older adults. Fifty-six healthy adults (mean age: 59.14 years) completed a standardized evaluation of physical fitness measurements (e.g., VO , push-ups, abdominal sit-ups, sit-and-reach, t test, and vertical jump). Fractional anisotropy (FA), an index of WM microstructure, was assessed using diffusion tensor imaging. The findings indicated that the cardiorespiratory fitness was positively associated with FA in the right cingulum hippocampus and the left cerebral peduncle. However, other physical fitness metrics were not significantly associated with FA in any region. These results suggest that cardiorespiratory fitness, but not other metrics of fitness, might be sensitive to WM microstructure.

摘要

本研究旨在探讨不同的身体适应能力测量指标与老年人的脑白质(WM)微观结构是否存在差异相关。56 名健康成年人(平均年龄:59.14 岁)完成了一项身体适应能力测量的标准化评估(例如,VO ,俯卧撑,仰卧起坐,坐立前伸,t 检验和垂直跳跃)。使用弥散张量成像评估了 WM 微观结构的各向异性分数(FA)。研究结果表明,心肺适能与右侧扣带回海马体和左侧大脑脚的 FA 呈正相关。但是,其他身体适应能力指标与任何区域的 FA 均无显著相关性。这些结果表明,心肺适能(而不是其他适应能力指标)可能对 WM 微观结构敏感。

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