Research Institute for Sustainable Chemistry , National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Higashi , Tsukuba , Ibaraki 305-8565 , Japan.
Hamamatsu Photonics K.K. , 314-5 Shimokanzo , Iwata , Shizuoka 438-0193 , Japan.
J Am Soc Mass Spectrom. 2020 Feb 5;31(2):298-307. doi: 10.1021/jasms.9b00048. Epub 2019 Dec 27.
The analysis of additives and polymers was performed by desorption ionization using through-hole alumina membrane (DIUTHAME) as a functional substrate for both sample pretreatment and surface-assisted laser desorption/ionization (SALDI) mass spectrometry. Using the unique absorbing/filtering capabilities of DIUTHAME and investigating the solubility of analytes/bulk materials in some solvents, three pretreatment techniques were demonstrated with (1) the selective removal of hydrophilic poly(ethylene oxide) (PEO)-based components from a "PEO-monostearate" sample, (2) the on-chip filtration of solubilized decabromodiphenylether (DBDE) from a solution of polystyrene that had been preliminarily precipitated, and (3) the on-chip extraction of antioxidants (Irganox 1010, Irgafos 168, and dimyristyl 3,3'-thiodipropionate) from a suspension of polypropylene powder or from the powder itself. The extracted analytes were further mass-analyzed using a spiral high-resolution time-of-flight analyzer to assess their elemental composition or molecular distribution.
通过使用通孔氧化铝膜 (DIUTHAME) 进行解吸电离分析，对添加剂和聚合物进行分析，DIUTHAME 既可用作样品预处理的功能基底，也可用作表面辅助激光解吸/电离 (SALDI) 质谱的功能基底。利用 DIUTHAME 的独特吸收/过滤功能，并研究分析物/散装材料在某些溶剂中的溶解度，展示了三种预处理技术：(1) 从“PEO-硬脂酸酯”样品中选择性去除亲水性聚(环氧乙烷) (PEO) 基成分，(2) 在初步沉淀的聚苯乙烯溶液中，在芯片上过滤溶解的十溴二苯醚 (DBDE)，以及 (3) 在芯片上从聚丙烯粉末悬浮液或粉末本身中提取抗氧化剂 (Irganox 1010、Irgafos 168 和二肉豆蔻基 3,3'-硫代二丙酸盐)。使用螺旋高分辨率飞行时间分析仪进一步对提取的分析物进行质量分析，以评估它们的元素组成或分子分布。
