Quon D, Fong T C, Mellor J, Brandschwei F H, Desautels J E
Dept. of Radiology and Diagnostic Imaging, University of Calgary School of Medicine, Alberta.
Can Assoc Radiol J. 1988 Dec;39(4):267-9.
Percutaneous needle biopsy is an accepted method of obtaining tissue for diagnosis of lung tumors. The depth of the lesion, size of the needle, operator experience, and the presence of emphysema have been identified as factors influencing the risk of postbiopsy pneumothorax, the most common complication. In this retrospective study of 308 patients, we enquired whether pulmonary function tests (available in 138 patients) and arterial PO2 (available in 103 patients) might predict the risk of pneumothorax following percutaneous needle biopsy. We found that as airway obstruction increases (FEV1.0/FVC less than 59% of predicted) or as arterial oxygenation decreases (PO2 less than 59 mm Hg), not only does the incidence of pneumothorax increase, but symptoms are more severe in that the number of pneumothoraces requiring chest tube drainage increases as well. We suggest that airway obstruction and arterial oxygenation are factors indicative of increased risk identifying patients who need close scrutiny after the procedure.
经皮针吸活检是获取组织以诊断肺部肿瘤的一种公认方法。病变深度、针的大小、操作者经验以及肺气肿的存在已被确定为影响活检后气胸（最常见的并发症）风险的因素。在这项对308例患者的回顾性研究中，我们探究了肺功能测试（138例患者可获得）和动脉血氧分压（103例患者可获得）是否可以预测经皮针吸活检后气胸的风险。我们发现，随着气道阻塞加重（第一秒用力呼气容积/用力肺活量低于预测值的59%）或动脉氧合降低（血氧分压低于59 mmHg），不仅气胸发生率增加，而且症状更严重，因为需要胸腔闭式引流的气胸数量也增加。我们认为气道阻塞和动脉氧合是提示风险增加的因素，可用于识别术后需要密切观察的患者。
