白喉加强疫苗在青少年炎症性肠病患者中的免疫原性。
Immunogenicity of Diphtheria Booster Vaccination in Adolescents With Inflammatory Bowel Disease.
机构信息
From the Department of Pediatric Gastroenterology and Nutrition, The Medical University of Warsaw, Warsaw, Poland.
Department and Clinic of Pediatrics, Gastroenterology and Nutrition, Wroclaw Medical University, Wroclaw, Poland.
出版信息
Pediatr Infect Dis J. 2020 Mar;39(3):244-246. doi: 10.1097/INF.0000000000002547.
The aim of this prospective study was to assess the immunogenicity and safety of booster vaccine against diphtheria in children with inflammatory bowel disease on and without immunosuppression treatment. Immunoprotection was achieved in 93% of the children. No significant differences depending on the treatment used and no serious adverse events or flares of inflammatory bowel disease were observed.
本前瞻性研究旨在评估免疫抑制和非免疫抑制治疗的炎症性肠病儿童接种白喉加强疫苗的免疫原性和安全性。93%的儿童获得了免疫保护。未观察到治疗方式相关的显著差异，也未观察到严重不良事件或炎症性肠病发作。
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