Medical Science Center, Federal University of Paraiba, João Pessoa, Brazil.
Postgraduate Program in Neuropsychiatry, Federal University of Pernambuco, Recife, Brazil.
World Neurosurg. 2020 May;137:e354-e357. doi: 10.1016/j.wneu.2020.01.209. Epub 2020 Feb 4.
To analyze the association between basilar invagination (BI) and stenosis in the hypoglossal canal (HC).
A case-control study with magnetic resonance images (MRIs) of the head from a local database was performed. The study used MRIs of 31 patients with BI (type B) and 36 controls, both groups over 18 years of age and without sex distinction. The internal (ID) and external (ED) diameters of the HC were measured on the coronal plane using the Osirix in its free version 3.9.2 (Mac-Apple platform). We used the Kolmogorov-Smirnov test (with Lilliefors adjustment) to evaluate the normality of the variables, the Levine test to verify the homogeneity of the variances, and Student's t test to verify differences between groups. All analyses were within the 95% confidence interval.
Control group presented right and left ED values of 4.7 ± 0.8 mm and 4.6 ± 0.9 mm, respectively, while the right and left ID showed 4.4 ± 0.9 mm and 4.3 ± 0.8 mm, respectively. The group with BI showed right and left ED values of 3.3 ± 0.9 mm and 3.1 ± 0.9 mm, and the right and left ID had values of 2.8 ± 0.7 mm and 2.7 ± 0.7 mm, respectively. Both ED and ID were smaller in the group with BI (P < 0.001).
Patients with BI of type B presented the narrowing of HC when compared with control participants.
分析颅底凹陷症（BI）与舌下神经管狭窄的相关性。
本研究采用病例对照设计，纳入了当地数据库中头部磁共振成像（MRI）的 31 例 BI（B 型）患者和 36 例对照组，两组患者年龄均大于 18 岁，且无性别差异。采用免费版 Osirix 3.9.2 软件（Mac-Apple 平台）在冠状面测量 HC 的内（ID）、外（ED）径。我们使用 Kolmogorov-Smirnov 检验（带 Lilliefors 校正）评估变量的正态性，使用 Levine 检验验证方差的同质性，使用 Student's t 检验验证组间差异。所有分析均在 95%置信区间内进行。
对照组右侧和左侧 ED 值分别为 4.7 ± 0.8mm 和 4.6 ± 0.9mm，ID 值分别为 4.4 ± 0.9mm 和 4.3 ± 0.8mm。BI 组右侧和左侧 ED 值分别为 3.3 ± 0.9mm 和 3.1 ± 0.9mm，ID 值分别为 2.8 ± 0.7mm 和 2.7 ± 0.7mm。BI 组的 ED 和 ID 均较小（P < 0.001）。
与对照组相比，B 型 BI 患者的 HC 变窄。
